dbPTM

ATE1_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ATE1_ARATH
UniProt AC	Q9ZT48
Protein Name	Arginyl-tRNA--protein transferase 1 {ECO:0000305}
Gene Name	ATE1 {ECO:0000303\|PubMed:9858543}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	632
Subcellular Localization
Protein Description	Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Component of the N-end rule pathway with ATE2 and PRT6. [PubMed: 19255443]
Protein Sequence	MSLKNDASSSHDGGSNRESVIDDHGRRKSTCGYCKSPARSSISHGLSAQTLTVYDYQALIDRGWRRSGTYLYKHEMDKTCCPPYTIRLKASDFVPTKEQQRVSRRLERFLDGKLDVQPREQRGASSSGDVSDTRRKTLGAAKSEENKKVEAVMDDLSKNIDQAVQLCIRSGEFPSNMQIPKASVKKVFCARRKKLAEGTEQILYTSNIAFPIAAAIKRIQTSEKEGINSAEGNRLSPETISEMLLSAMHKVGETPDVSIKVCKGHINFLSSAKDSFSDRDVVPNGNISRGANSLDGSETLHAKKDSENHQARKRKLEIHLKRSSFDPEEHELYKRYQLKVHNDKPGHVVESSYRRFLVDSPLIDVQPSGDEKVPPCGFGSFHQQYRIDGRLIAVGVVDILPKCLSSVYLFWDPDYAFLSLGKYSAIQEINWVIENQARCPSLQYYYLGYYIHSCSKMRYKAAYRPSELLCPLRFQWVPFEVARPMLDKKPYVILSDIAISHNQCSLLAGASETLVEPAASEHEDMEQGETNDNFMGCSDEDEDEDEDDDDDDDDDEEMYETESEDSHIESDPGSKDNDINNILIGLYGSQYRYKEMRQIITPVGRKQLEPMLQSYRKVVGAELSERMVYEIN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
126	Phosphorylation	REQRGASSSGDVSDT HHHCCCCCCCCCHHH	37.49	25561503
127	Phosphorylation	EQRGASSSGDVSDTR HHCCCCCCCCCHHHH	36.20	29654922
275	Phosphorylation	FLSSAKDSFSDRDVV HHHCCCCCCCCCCCC	26.41	25561503
277	Phosphorylation	SSAKDSFSDRDVVPN HCCCCCCCCCCCCCC	35.37	25561503
293	Phosphorylation	NISRGANSLDGSETL CCCCCCCCCCCCCCH	27.57	30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ATE1_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ATE1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ATE1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ATE1_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ATE1_ARATH

Related Literatures of Post-Translational Modification