AT2B3_RAT - dbPTM
AT2B3_RAT - PTM Information in dbPTM
Basic Information of Protein
UniProt ID AT2B3_RAT
UniProt AC Q64568
Protein Name Plasma membrane calcium-transporting ATPase 3
Gene Name Atp2b3
Organism Rattus norvegicus (Rat).
Sequence Length 1258
Subcellular Localization Cell membrane
Multi-pass membrane protein.
Protein Description This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell..
Protein Sequence MGDMANSSIEFHPKPQQQREVPHVGGFGCTLAELRSLMELRGAEALQKIQEAYGDVSGLCRRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQGNDLKIDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANVPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVDGRVWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFILDLKRDFQPVREQIPEDQLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVKKIIEPMACDGLRTICIAYRDFSAIQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLTIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILWFRGLNRIQTQMEVVSTFKRSGSFQGAVRRRSSVLSQLHDVTNLSTPTHIRVVKAFRSSLYEGLEKPESKSCIHNFMATPEFLINDYTHNIPLIDDTDVDENEERLRAPPPPPPNQNNNAIDSGIYLTTHATKSATSSAFSSRPGSPLHSMETSL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Phosphorylation-MGDMANSSIEFHPK
-CCCCCCCCCCCCCC		24.1322673903
8PhosphorylationMGDMANSSIEFHPKP
CCCCCCCCCCCCCCH		26.4122673903
14AcetylationSSIEFHPKPQQQREV
CCCCCCCCHHHCCCC		47.0622902405
36PhosphorylationCTLAELRSLMELRGA
CHHHHHHHHHHHHCH		44.7022673903
75PhosphorylationTEGLADNTNDLEKRR
CCCCCCCCCHHHHHH		30.5630181290
572AcetylationIPEDQLYKVYTFNSV
CCHHHCEEEEEHHHH		37.04-
578PhosphorylationYKVYTFNSVRKSMST
EEEEEHHHHHHHCCE		21.0725403869
744UbiquitinationNRRIRNEKGEIEQER
HHHHHCCCCCHHHHH		66.45-
744AcetylationNRRIRNEKGEIEQER
HHHHHCCCCCHHHHH		66.4513578745
758UbiquitinationRLDKVWPKLRVLARS
HHHHHHHHHHHHHCC		32.96-
765PhosphorylationKLRVLARSSPTDKHT
HHHHHHCCCCCCHHH		34.7525403869
766PhosphorylationLRVLARSSPTDKHTL
HHHHHCCCCCCHHHH		26.6825403869
768PhosphorylationVLARSSPTDKHTLVK
HHHCCCCCCHHHHEE		60.6825403869
803UbiquitinationTNDGPALKKADVGFA
CCCCHHHHHCCCEEE		48.28-
804UbiquitinationNDGPALKKADVGFAM
CCCHHHHHCCCEEEH		51.15-
918AcetylationRKPYGRDKPLISRTM
CCCCCCCCCCCCHHH		40.1222902405
1079PhosphorylationGPGKDEMTDEELAEG
CCCCCCCCHHHHHHC		37.9130240740
1113PhosphorylationRGLNRIQTQMEVVST
HCCCHHHHHHHHHHH		27.75-
1121 (in isoform 7)Phosphorylation-4.8828432305
1122 (in isoform 7)Phosphorylation-45.8228432305
1124PhosphorylationVVSTFKRSGSFQGAV
HHHHHCCCCCCHHHH		39.1028551015
1125 (in isoform 7)Phosphorylation-36.1928432305
1126PhosphorylationSTFKRSGSFQGAVRR
HHHCCCCCCHHHHHH		18.6830411139
1134 (in isoform 3)Phosphorylation-23.7928432305
1134 (in isoform 10)Phosphorylation-23.7928432305
1135 (in isoform 10)Phosphorylation-24.0028432305
1135 (in isoform 6)Phosphorylation-24.0028432305
1135 (in isoform 3)Phosphorylation-24.0028432305
1135PhosphorylationQGAVRRRSSVLSQLH
HHHHHHHHHHHHHHH		24.0027115346
1136 (in isoform 6)Phosphorylation-25.8528432305
1136PhosphorylationGAVRRRSSVLSQLHD
HHHHHHHHHHHHHHC		25.8527115346
1139 (in isoform 6)Phosphorylation-28.6528432305
1148 (in isoform 2)Phosphorylation-34.1228432305
1148 (in isoform 9)Phosphorylation-34.1228432305
1149 (in isoform 2)Phosphorylation-35.0628432305
1149 (in isoform 9)Phosphorylation-35.0628432305
1161PhosphorylationRVVKAFRSSLYEGLE
HHHHHHHHHHHHCCC		20.4528432305
1162PhosphorylationVVKAFRSSLYEGLEK
HHHHHHHHHHHCCCC		30.6228432305
1164PhosphorylationKAFRSSLYEGLEKPE
HHHHHHHHHCCCCCC		15.2028432305
1240PhosphorylationHATKSATSSAFSSRP
CCCCCCCCHHHCCCC		21.2728432305
1241PhosphorylationATKSATSSAFSSRPG
CCCCCCCHHHCCCCC		29.0428432305
1244PhosphorylationSATSSAFSSRPGSPL
CCCCHHHCCCCCCCC		25.7528432305
1245PhosphorylationATSSAFSSRPGSPLH
CCCHHHCCCCCCCCH		35.7228432305
1249PhosphorylationAFSSRPGSPLHSMET
HHCCCCCCCCHHCCC		27.2828432305
1253PhosphorylationRPGSPLHSMETSL--
CCCCCCHHCCCCC--		26.4628432305
1256PhosphorylationSPLHSMETSL-----
CCCHHCCCCC-----		27.0428432305
1257PhosphorylationPLHSMETSL------
CCHHCCCCC------		20.8328432305
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
1113TPhosphorylationKinasePKC-Uniprot
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of AT2B3_RAT !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of AT2B3_RAT !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of AT2B3_RAT !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of AT2B3_RAT

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory