ARPC5_MOUSE - dbPTM
ARPC5_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ARPC5_MOUSE
UniProt AC Q9CPW4
Protein Name Actin-related protein 2/3 complex subunit 5
Gene Name Arpc5
Organism Mus musculus (Mouse).
Sequence Length 151
Subcellular Localization Cytoplasm, cytoskeleton. Cell projection.
Protein Description Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks..
Protein Sequence MSKNTVSSARFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDNSSAVLLQWHEKALAAGGVGSIVRVLTARKTV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MSKNTVSSA
------CCCCCCCCC
34.31-
2Phosphorylation------MSKNTVSSA
------CCCCCCCCC
34.3130635358
3Malonylation-----MSKNTVSSAR
-----CCCCCCCCCC
56.1726320211
7Phosphorylation-MSKNTVSSARFRKV
-CCCCCCCCCCEEEC
19.0823375375
8PhosphorylationMSKNTVSSARFRKVD
CCCCCCCCCCEEECC
21.0823375375
13UbiquitinationVSSARFRKVDVDEYD
CCCCCEEECCHHHCC
39.8222790023
19PhosphorylationRKVDVDEYDENKFVD
EECCHHHCCCCCCCC
24.8825159016
67UbiquitinationKNPPINTKSQAVKDR
HCCCCCCCHHHHHHH
35.7622790023
77PhosphorylationAVKDRAGSIVLKVLI
HHHHHHHHHHHHHHH
14.4527180971
87UbiquitinationLKVLISFKANDIEKA
HHHHHHCHHCHHHHH
39.2222790023
93AcetylationFKANDIEKAVQSLDK
CHHCHHHHHHHHHHH
54.9422826441
93UbiquitinationFKANDIEKAVQSLDK
CHHCHHHHHHHHHHH
54.9422790023
112UbiquitinationLLMKYIYKGFESPSD
HHHHHHHHCCCCCCC
47.7922790023
112AcetylationLLMKYIYKGFESPSD
HHHHHHHHCCCCCCC
47.7922826441
116PhosphorylationYIYKGFESPSDNSSA
HHHHCCCCCCCCCCH
27.6925338131
131UbiquitinationVLLQWHEKALAAGGV
HHHHHHHHHHHCCCH
35.4922790023
146PhosphorylationGSIVRVLTARKTV--
HHHHHHHHCCCCC--
22.8924719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ARPC5_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ARPC5_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ARPC5_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ARPC5_MOUSE !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ARPC5_MOUSE

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Related Literatures of Post-Translational Modification

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