ARPC4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ARPC4_SCHPO
• UniProt AC: Q92352
• Protein Name: Actin-related protein 2/3 complex subunit 4
• Gene Name: arc4
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 168
• Subcellular Localization: Cytoplasm, cytoskeleton, actin patch.
• Protein Description: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity)..
• Protein Sequence: MSNTLRPYLNAVRSTLTASLALEEFSSEIVERQSQPEVEVGRSPEILLKPLVVSRNEQEQCLIESSVNSVRFSIRIKQVDEIERILVRKFMQFLMGRAESFFILRRKPVQGYDISFLITNYHTEEMLKHKLVDFIIEFMEEVDAEISEMKLFLNGRARLVAETYLSCF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	Phosphorylation	PEVEVGRSPEILLKP CCCCCCCCHHHHHEE	22.43	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ARPC4_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ARPC4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ARPC4_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of ARPC4_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.