ARPC2_MOUSE - dbPTM
ARPC2_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ARPC2_MOUSE
UniProt AC Q9CVB6
Protein Name Actin-related protein 2/3 complex subunit 2
Gene Name Arpc2
Organism Mus musculus (Mouse).
Sequence Length 300
Subcellular Localization Cytoplasm, cytoskeleton. Cell projection. Cell junction, synapse, synaptosome .
Protein Description Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity)..
Protein Sequence MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGADELLKRVYGSFLVNPEPGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNATARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
65AcetylationSISLKFYKELQAHGA
EEEHHHHHHHHHCCH		55.8923864654
65UbiquitinationSISLKFYKELQAHGA
EEEHHHHHHHHHCCH		55.89-
77AcetylationHGADELLKRVYGSFL
CCHHHHHHHHHHHHH		53.0623954790
108PhosphorylationNLPASKDSIVHQAGM
CCCCCCCHHHHHHHH		30.1922802335
136AcetylationFQFQEEGKEGENRAV
HHHHHCCCCCCCEEE		66.8622826441
136UbiquitinationFQFQEEGKEGENRAV
HHHHHCCCCCCCEEE		66.86-
186AcetylationKVFMQEFKEGRRASH
EHHHHHHHCCCCCCC		59.5122826441
186MalonylationKVFMQEFKEGRRASH
EHHHHHHHCCCCCCC		59.5126320211
192PhosphorylationFKEGRRASHTAPQVL
HHCCCCCCCCCCCHH		21.4028833060
240PhosphorylationNATARDNTINLIHTF
CCCCCCCEEEHHHHH		18.6126370283
257GlutathionylationYLHYHIKCSKAYIHT
HHHHHHEECCCCHHH		5.0924333276
261PhosphorylationHIKCSKAYIHTRMRA
HHEECCCCHHHHHHH		9.2925367039
275UbiquitinationAKTSDFLKVLNRARP
HCHHHHHHHHHHHCC		44.67-
275MalonylationAKTSDFLKVLNRARP
HCHHHHHHHHHHHCC		44.6726320211
275AcetylationAKTSDFLKVLNRARP
HCHHHHHHHHHHHCC		44.6722826441
290UbiquitinationDAEKKEMKTITGKTF
CHHHHHHHHHCCCCC		37.5627667366
290MalonylationDAEKKEMKTITGKTF
CHHHHHHHHHCCCCC		37.5626320211
290AcetylationDAEKKEMKTITGKTF
CHHHHHHHHHCCCCC		37.5622902405
295UbiquitinationEMKTITGKTFSSR--
HHHHHCCCCCCCC--		37.4327667366
295AcetylationEMKTITGKTFSSR--
HHHHHCCCCCCCC--		37.43-
296PhosphorylationMKTITGKTFSSR---
HHHHCCCCCCCC---		30.0529176673
298PhosphorylationTITGKTFSSR-----
HHCCCCCCCC-----		30.3629514104
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ARPC2_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ARPC2_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ARPC2_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ARPC2_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ARPC2_MOUSE

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Related Literatures of Post-Translational Modification

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