dbPTM

ARP7_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ARP7_ARATH
UniProt AC	Q8L4Y5
Protein Name	Actin-related protein 7
Gene Name	ARP7
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	363
Subcellular Localization	Nucleus . Cytoplasm . Localized in the nucleus during the interphase, but is released into the cytoplasm during the mitotic phase (PubMed:12609034).
Protein Description	Essential protein required during embryogenesis and all plant development stages, probably through a chromatin-mediated regulation of gene expression..
Protein Sequence	MEALVVDAGSKFLKAGAAIPDQSPAMIIPSQMKRMVDDGSSSADNPTTVFEDVTLDPIERGLIRDWDAMEDLLRYVVYTGLGWEEGNEGNILFTDPLCTPKAIREQLVQLMFETFNVSGFYASEQAVLSLYAVGRISGCTVDIGHGKIDIAPVLEGAVQHIASKRFELGGTELTKLFAQELGKTNPSMNLSMSDVEKLKEQYANCAEDEIAYKKTQNCEIEQHTLPDGQVISIGRERYSVGEALFQPSILGLEEHGIVEQLVRIISTVSSENHRQLLENTVLCGGTTSMTGFESRFQKEANLCSSAIRPTLVKPPEYMPENLGMYSAWVGGAILAKVVFPQNQHVTKADYDETGPSVVHRKCF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MEALVVDA -------CCEEEECC	6.49	22223895
40	Phosphorylation	KRMVDDGSSSADNPT CHHHCCCCCCCCCCC	28.28	23776212
41	Phosphorylation	RMVDDGSSSADNPTT HHHCCCCCCCCCCCE	34.77	23776212
42	Phosphorylation	MVDDGSSSADNPTTV HHCCCCCCCCCCCEE	41.14	23776212
47	Phosphorylation	SSSADNPTTVFEDVT CCCCCCCCEEEECCC	41.67	23776212
48	Phosphorylation	SSADNPTTVFEDVTL CCCCCCCEEEECCCC	25.18	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ARP7_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ARP7_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ARP7_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ARP7_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ARP7_ARATH

Related Literatures of Post-Translational Modification