ARP5L_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ARP5L_MOUSE
• UniProt AC: Q9D898
• Protein Name: Actin-related protein 2/3 complex subunit 5-like protein
• Gene Name: Arpc5l
• Organism: Mus musculus (Mouse).
• Sequence Length: 153
• Subcellular Localization: Cytoplasm, cytoskeleton.
• Protein Description: May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks..
• Protein Sequence: MARNTLSSRFRRVDIDEFDENKFVDEHEEAAAAAGEPGPDPCEVDGLLRQGDMLRAFHAALRNSPINTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MARNTLSSRFRR ---CCCCHHHHHHHC	23.59	23737553
7	Phosphorylation	-MARNTLSSRFRRVD -CCCCHHHHHHHCCC	19.89	23737553
8	Phosphorylation	MARNTLSSRFRRVDI CCCCHHHHHHHCCCH	38.25	23737553
17	Ubiquitination	FRRVDIDEFDENKFV HHCCCHHHCCCCCCC	56.16	27667366
64	Phosphorylation	FHAALRNSPINTKNQ HHHHHHCCCCCCCCH	22.26	25521595
68	Phosphorylation	LRNSPINTKNQAVKE HHCCCCCCCCHHHHH	31.90	25159016
69	Ubiquitination	RNSPINTKNQAVKER HCCCCCCCCHHHHHH	42.44	27667366
69	Malonylation	RNSPINTKNQAVKER HCCCCCCCCHHHHHH	42.44	26320211
86	Phosphorylation	GVVLKVLTNFKSSEI HHHHHHHHHCCHHHH	41.41	20415495
89	Ubiquitination	LKVLTNFKSSEIEQA HHHHHHCCHHHHHHH	55.96	-
90	Phosphorylation	KVLTNFKSSEIEQAV HHHHHCCHHHHHHHH	29.12	25521595
91	Phosphorylation	VLTNFKSSEIEQAVQ HHHHCCHHHHHHHHH	43.09	29472430
110	Ubiquitination	NGIDLLMKYIYKGFE CCHHHHHHHHHHCCC	28.59	-
148	Phosphorylation	GSIIRVLTARKTV-- HHHHHHHHHCCCC--	22.89	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ARP5L_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ARP5L_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ARP5L_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ARP5L_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.