ARMC8_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ARMC8_MOUSE
• UniProt AC: Q9DBR3
• Protein Name: Armadillo repeat-containing protein 8
• Gene Name: Armc8
• Organism: Mus musculus (Mouse).
• Sequence Length: 673
• Protein Sequence: MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSPSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDSCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETETMMDRIVTGSSESSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDMNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHSIEVKEQTLCILANIADGTTAKELIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLTWNEEEGSQERQDKLRDMGIVDILHKLSQSADSNLCDKAKTALQQYLA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MACLLETPI ------CCCCCCCCC	7.83	-
7	Phosphorylation	-MACLLETPIRMSVL -CCCCCCCCCCHHHH	24.80	24719451
20	Phosphorylation	VLSEVTASSRHYVDR HHHHHCCCCCCHHHH	20.66	24719451
21	Phosphorylation	LSEVTASSRHYVDRL HHHHCCCCCCHHHHH	22.17	24719451
337	Phosphorylation	DYFKYPSSVSAITDI HHHCCCCCCHHHHHH	18.65	-
391	Phosphorylation	TMMDRIVTGSSESSV HHHHHHHCCCCCHHH	29.04	17203969
393	Phosphorylation	MDRIVTGSSESSVKV HHHHHCCCCCHHHHH	22.90	17203969
394	Phosphorylation	DRIVTGSSESSVKVR HHHHCCCCCHHHHHH	42.73	17203969
396	Phosphorylation	IVTGSSESSVKVRLA HHCCCCCHHHHHHHH	42.24	17203969
397	Phosphorylation	VTGSSESSVKVRLAA HCCCCCHHHHHHHHH	23.16	17203969
510	Phosphorylation	IKADILRSLSTEQLF HHHHHHHCCCHHHHH	24.19	28066266
512	Phosphorylation	ADILRSLSTEQLFRL HHHHHCCCHHHHHHH	31.01	22817900
513	Phosphorylation	DILRSLSTEQLFRLL HHHHCCCHHHHHHHH	32.80	28066266
610	Phosphorylation	IKYYMGHSHVKLQLA HHHHHCCCCHHHHHH	25.01	25338131
651	Ubiquitination	GIVDILHKLSQSADS CHHHHHHHHHCCCCC	46.52	-
663	Ubiquitination	ADSNLCDKAKTALQQ CCCCHHHHHHHHHHH	51.27	-
665	Ubiquitination	SNLCDKAKTALQQYL CCHHHHHHHHHHHHH	39.82	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ARMC8_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ARMC8_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ARMC8_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ARMC8_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Protein phosphorylation and expression profiling by Yin-yangmultidimensional liquid chromatography (Yin-yang MDLC) massspectrometry.";
Dai J., Jin W.-H., Sheng Q.-H., Shieh C.-H., Wu J.-R., Zeng R.;
J. Proteome Res. 6:250-262(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-391, AND MASSSPECTROMETRY.
PubMed: 17203969