dbPTM

ARMC6_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ARMC6_DROME
UniProt AC	Q7K486
Protein Name	Armadillo repeat-containing protein 6 homolog
Gene Name	CG5721
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	464
Subcellular Localization
Protein Description
Protein Sequence	MAKVISQDTFDDVVKENVVEFSMTPSEAKEETIKQFEAQGINLANIIKDLSVNPQTGQPVINETVDKIKEHIGQKLEETTELLEQLATLDAECKKSLAHRVLAGKNGAHDALITLLEETLSAESPNESVLKKSLEAINSLTHKQPDLFDAEAMAVVLKLLALKVESEEVTLLTLQWLQKACIMHEMNRQNIMNTSALKLMKPLLGKGKDRLVRELTAVFRFLVLDDDIRVEFGCAHEHARQIAGEVLITLVELLPAYQDPNVLADLLLTIGTLAVRQELCTAIDEAGGLKSVFEIMSSNLDEVRLNREALKLLRALAGQDSVKSHIVQQGVAPIIKQLLETHQSNENIVAAALACVTTLTLRVQEHSAAFFDTGIAEVIVEALRAHPKHKIVQRNGAWAIRNMVSRSRNQCETWISFGVEDLLNMAMKEHPSVEQDIKAALRDLGCSVHLREEWTGTAEKKIAA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	AKVISQDTFDDVVKE CCCCCCCCHHHHHHH	22.71	18327897
311	Acetylation	RLNREALKLLRALAG HHCHHHHHHHHHHCC	53.15	21791702
457	Phosphorylation	LREEWTGTAEKKIAA ECCCCCCCCCHHHCC	25.03	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ARMC6_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ARMC6_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ARMC6_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ARMC6_DROME !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ARMC6_DROME

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of Drosophila melanogaster embryos."; Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.; J. Proteome Res. 7:1675-1682(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-9, AND MASSSPECTROMETRY.	18327897 [Abstract]