ARL8B_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ARL8B_RAT
• UniProt AC: Q66HA6
• Protein Name: ADP-ribosylation factor-like protein 8B
• Gene Name: Arl8b
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 186
• Subcellular Localization: Late endosome membrane . Lysosome membrane . Cytoplasm, cytoskeleton, spindle . Localizes with microtubules at the spindle mid-zone during mitosis.
• Protein Description: May play a role in lysosome motility. May play a role in chromosome segregation..
• Protein Sequence: MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
62	Ubiquitination	FNMRKVTKGNVTIKI EEEEEECCCCEEEEE	52.02	-
68	Ubiquitination	TKGNVTIKIWDIGGQ CCCCEEEEEEECCCC	28.51	-
141	Acetylation	LPNALDEKQLIEKMN CCCCCCHHHHHHHCC	50.50	22902405
141	Ubiquitination	LPNALDEKQLIEKMN CCCCCCHHHHHHHCC	50.50	-
150	Phosphorylation	LIEKMNLSAIQDREI HHHHCCHHHHCCCEE	20.51	27097102

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ARL8B_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ARL8B_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ARL8B_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of ARL8B_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.