dbPTM

ARL8B_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ARL8B_MOUSE
UniProt AC	Q9CQW2
Protein Name	ADP-ribosylation factor-like protein 8B
Gene Name	Arl8b
Organism	Mus musculus (Mouse).
Sequence Length	186
Subcellular Localization	Late endosome membrane . Lysosome membrane . Cytoplasm, cytoskeleton, spindle . Localizes with microtubules at the spindle mid-zone during mitosis.
Protein Description	May play a role in lysosome motility. May play a role in chromosome segregation..
Protein Sequence	MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
30	Phosphorylation	LTLVGLQYSGKTTFV EEEEEEEECCCEEEE	25.16	-
31	Phosphorylation	TLVGLQYSGKTTFVN EEEEEEECCCEEEEE	22.35	-
62	Ubiquitination	FNMRKVTKGNVTIKI EEEEEECCCCEEEEE	52.02	22790023
141	Acetylation	LPNALDEKQLIEKMN CCCCCCHHHHHHHCC	50.50	23954790
141	Ubiquitination	LPNALDEKQLIEKMN CCCCCCHHHHHHHCC	50.50	22790023
146	Ubiquitination	DEKQLIEKMNLSAIQ CHHHHHHHCCHHHHC	26.54	22790023
150	Phosphorylation	LIEKMNLSAIQDREI HHHHCCHHHHCCCEE	20.51	28066266
182	Ubiquitination	QWLIQHSKSRRS--- HHHHHHHHHCCC---	45.95	22790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ARL8B_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ARL8B_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ARL8B_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ARL8B_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ARL8B_MOUSE

Related Literatures of Post-Translational Modification