ARL4D_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ARL4D_MOUSE
• UniProt AC: Q99PE9
• Protein Name: ADP-ribosylation factor-like protein 4D
• Gene Name: Arl4d
• Organism: Mus musculus (Mouse).
• Sequence Length: 201
• Subcellular Localization: Nucleus, nucleolus. Cell membrane . Nucleus. Cytoplasm.
• Protein Description: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form (By similarity)..
• Protein Sequence: MGNHLTEMAPTASSFLPHFQALHVVVIGLDSAGKTSLLYRLKFKEFVQSVPTKGFNTEKIRVPLGGSRGITFQVWDVGGQEKLRPLWRSYTRRTDGLVFVVDSAETERLEEARMELHRISKASDNQGVPVLVLANKQDQPGALSAAEVEKRLAVRELAAATLTHVQGCSAVDGLGLQPGLEHLYEMILKRKKAPRSSKKRR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGNHLTEMA ------CCCCHHHCC	30.20	-
121	Ubiquitination	MELHRISKASDNQGV HHHHHHHHCCCCCCC	49.92	27667366

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ARL4D_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ARL4D_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ARL4D_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ARL4D_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.