ARIP4_MOUSE - dbPTM
ARIP4_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ARIP4_MOUSE
UniProt AC Q99NG0
Protein Name Helicase ARIP4
Gene Name Rad54l2
Organism Mus musculus (Mouse).
Sequence Length 1466
Subcellular Localization Nucleus . Localizes in speckle-like nuclear compartments.
Protein Description DNA helicase that modulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. Not able to remodel mononucleosomes in vitro. Acts as an AR-coregulator in Sertoli cells..
Protein Sequence MSDESASGSDPDLDPDVELEDEEEEEEEEEVAVEEHDRDDEEGLLDDTSLEGMCGTEHAQLGEDGQRPPRCTSTTSSQSEPSEQLRHQGKILASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQRKEYAAPIPTVPLEFLPEEIVLRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEVIELSSGEEDTLHIVDSSESVSEEDEEEEKGGTHVNDALNQHDALGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPAPEALPADSKPEEVQPRFFKVHILNDEHKTVASRAKVTADWVSEGGVLLMGYEMYRLLTLKKSLATSRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSQIQRDLYTQFMDRFRDCGTSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKENLANEQDLDVEELGSAGTSARCPPHGTKVKGEDSALPSSMGEATNSKFLQGVGFNPFQERGNNIVTYEWAKELLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKRDMPCLPGAEGQGTQKWVRNVSYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCHIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHFVEKEPAPQTSLDIKGIKESVLQLACLKYPHLITKEPFEHESLLLNRKDHKLTKAEKKAAKKSYEEDKRTSVPYTRPSYAQYYPASDQSLTSIPAFSQRNWQPTLKGDEKPVASVRPVQSTPIPMMPRHVPLSGGVSSASSTNTSMNFPINYLQRAGVLVQKVVTTTDIVIPGLNSSTDVQARINAGESIHIIRGTKGTYIRTSDGRIFAVRATGKPKAPEDGRMAASGSQGPSLASTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAAARESRQSSPSISAALPGPPGQLMDNSTIPGTALGTEPCLGGHCLNSSLLVTGQPSGGRHPVLDLRGHKRKLATPSVTQESIRRRSRKGHLPAPVQPYEHGYPVSGGFAMPPVSLNHNLTTPFTSQAGENSLFMGSNPSYYQLSNLLADARLVFPVTTDPLVPAGPVSSSSTATSVTASNPSFMLNPSVPGMLPSYSLPFSQPLLSEPRMFAPFPSPGLPSNLSRGVSVYPGYMSPHAGYPAGGLLRSQVPPFDSHEVAEVGFSSNDDEDKDDDVIEVTGK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
72PhosphorylationGQRPPRCTSTTSSQS
CCCCCCCCCCCCCCC		30.3228066266
73PhosphorylationQRPPRCTSTTSSQSE
CCCCCCCCCCCCCCC		33.0628066266
74PhosphorylationRPPRCTSTTSSQSEP
CCCCCCCCCCCCCCC		16.7328066266
75PhosphorylationPPRCTSTTSSQSEPS
CCCCCCCCCCCCCCC		26.5828066266
76PhosphorylationPRCTSTTSSQSEPSE
CCCCCCCCCCCCCCH		26.8628066266
77PhosphorylationRCTSTTSSQSEPSEQ
CCCCCCCCCCCCCHH		35.3228066266
79PhosphorylationTSTTSSQSEPSEQLR
CCCCCCCCCCCHHHH		54.1228066266
82PhosphorylationTSSQSEPSEQLRHQG
CCCCCCCCHHHHHHC		33.6428066266
282PhosphorylationIGGIRFLYDNLVESL
CCCCHHHHHHHHHHH		10.48-
583PhosphorylationNVILVRLSQIQRDLY
CEEEEEHHHHHHHHH		18.0519854140
591PhosphorylationQIQRDLYTQFMDRFR
HHHHHHHHHHHHHHH		23.7219854140
602PhosphorylationDRFRDCGTSGWLGLN
HHHHHCCCCCCCCCC		30.3319854140
874PhosphorylationYTLEKKIYDRQISKQ
CCHHHHHHCHHHHHC		17.6030352176
970PhosphorylationEKKAAKKSYEEDKRT
HHHHHHHHHHHHHCC		36.7527841257
971PhosphorylationKKAAKKSYEEDKRTS
HHHHHHHHHHHHCCC		32.0227841257
1151PhosphorylationSTSNGRHSASSPKAP
CCCCCCCCCCCCCCC		28.6019060867
1153PhosphorylationSNGRHSASSPKAPDP
CCCCCCCCCCCCCCC		50.6321183079
1154PhosphorylationNGRHSASSPKAPDPE
CCCCCCCCCCCCCCC		30.0921183079
1168PhosphorylationEGLARPVSPDSPEII
CCCCCCCCCCCHHHH		26.1821082442
1171PhosphorylationARPVSPDSPEIISEL
CCCCCCCCHHHHHHH		28.0221082442
1176PhosphorylationPDSPEIISELQQYAD
CCCHHHHHHHHHHHH		37.6026643407
1181PhosphorylationIISELQQYADVAAAR
HHHHHHHHHHHHHHH		7.5725293948
1259PhosphorylationGHKRKLATPSVTQES
CCCCCCCCCCCCHHH		26.9129514104
1413PhosphorylationSNLSRGVSVYPGYMS
CCCCCCCEECCCCCC		20.8229472430
1415PhosphorylationLSRGVSVYPGYMSPH
CCCCCEECCCCCCCC		5.3923984901
1418PhosphorylationGVSVYPGYMSPHAGY
CCEECCCCCCCCCCC		7.0123984901
1420PhosphorylationSVYPGYMSPHAGYPA
EECCCCCCCCCCCCC		12.6826745281
1425PhosphorylationYMSPHAGYPAGGLLR
CCCCCCCCCCCCCHH		7.2423984901
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ARIP4_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ARIP4_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ARIP4_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ARIP4_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ARIP4_MOUSE

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Related Literatures of Post-Translational Modification

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