UniProt ID | ARG39_HUMAN | |
---|---|---|
UniProt AC | Q8N4T4 | |
Protein Name | Rho guanine nucleotide exchange factor 39 | |
Gene Name | ARHGEF39 | |
Organism | Homo sapiens (Human). | |
Sequence Length | 335 | |
Subcellular Localization | Cell membrane . | |
Protein Description | Promotes cell proliferation.. | |
Protein Sequence | MELSCPGSRCPVQEQRARWERKRACTARELLETERRYQEQLGLVATYFLGILKAKGTLRPPERQALFGSWELIYGASQELLPYLEGGCWGQGLEGFCRHLELYNQFAANSERSQTTLQEQLKKNKGFRRFVRLQEGRPEFGGLQLQDLLPLPLQRLQQYENLVVALAENTGPNSPDHQQLTRAARLISETAQRVHTIGQKQKNDQHLRRVQALLSGRQAKGLTSGRWFLRQGWLLVVPPHGEPRPRMFFLFTDVLLMAKPRPPLHLLRSGTFACKALYPMAQCHLSRVFGHSGGPCGGLLSLSFPHEKLLLMSTDQEELSRWYHSLTWAISSQKN | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
4 | Phosphorylation | ----MELSCPGSRCP ----CCCCCCCCCCC | 21955146 | ||
10 | Phosphorylation | LSCPGSRCPVQEQRA CCCCCCCCCHHHHHH | 32645325 | ||
33 | Phosphorylation | TARELLETERRYQEQ HHHHHHHHHHHHHHH | - | ||
86 (in isoform 2) | Ubiquitination | - | 21906983 | ||
110 | Phosphorylation | YNQFAANSERSQTTL HHHHHCCCHHHHHHH | 25627689 | ||
113 | Phosphorylation | FAANSERSQTTLQEQ HHCCCHHHHHHHHHH | 24275569 | ||
122 | Ubiquitination | TTLQEQLKKNKGFRR HHHHHHHHHCCCHHH | 2190698 | ||
122 (in isoform 1) | Ubiquitination | - | 21906983 | ||
122 (in isoform 3) | Ubiquitination | - | 21906983 | ||
122 (in isoform 4) | Ubiquitination | - | 21906983 | ||
200 | Ubiquitination | RVHTIGQKQKNDQHL HHHHHCHHHCCHHHH | 27667366 | ||
232 | Ubiquitination | GRWFLRQGWLLVVPP CCEEEECCEEEEECC | 22505724 | ||
275 | Ubiquitination | RSGTFACKALYPMAQ CCCCCHHHHHHHHHH | 22505724 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ARG39_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ARG39_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ARG39_HUMAN !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
TIFA_HUMAN | TIFA | physical | 25416956 |
Kegg Disease | ||||||
---|---|---|---|---|---|---|
There are no disease associations of PTM sites. | ||||||
OMIM Disease | ||||||
There are no disease associations of PTM sites. | ||||||
Kegg Drug | ||||||
There are no disease associations of PTM sites. | ||||||
DrugBank | ||||||
There are no disease associations of PTM sites. |
loading...