ARF3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ARF3_MOUSE
• UniProt AC: P61205
• Protein Name: ADP-ribosylation factor 3
• Gene Name: Arf3
• Organism: Mus musculus (Mouse).
• Sequence Length: 181
• Subcellular Localization: Golgi apparatus. Cytoplasm, perinuclear region.
• Protein Description: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus..
• Protein Sequence: MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGNIFGNLL ------CCCHHHHHH	35.62	-
15	Ubiquitination	LLKSLIGKKEMRILM HHHHHCCCHHEEEEE	38.27	-
35	Phosphorylation	AGKTTILYKLKLGEI CCCEEEEEEEECCCE	15.49	-
36	Ubiquitination	GKTTILYKLKLGEIV CCEEEEEEEECCCEE	35.38	-
36	Succinylation	GKTTILYKLKLGEIV CCEEEEEEEECCCEE	35.38	23806337
36	Acetylation	GKTTILYKLKLGEIV CCEEEEEEEECCCEE	35.38	23806337
38	Ubiquitination	TTILYKLKLGEIVTT EEEEEEEECCCEEEE	50.74	-
38	Acetylation	TTILYKLKLGEIVTT EEEEEEEECCCEEEE	50.74	22826441
59	Ubiquitination	NVETVEYKNISFTVW EEEEEEEEEEEEEEE	34.01	-
62	Phosphorylation	TVEYKNISFTVWDVG EEEEEEEEEEEEECC	25.02	22817900
73	Acetylation	WDVGGQDKIRPLWRH EECCCCCCCHHHHHH	32.50	23806337
73	Ubiquitination	WDVGGQDKIRPLWRH EECCCCCCCHHHHHH	32.50	-
127	Ubiquitination	VLLVFANKQDLPNAM HHHHEECCCCCCCCC	41.58	22790023
140	Phosphorylation	AMNAAEITDKLGLHS CCCHHHHHHHHCCHH	20.70	20415495
142	Ubiquitination	NAAEITDKLGLHSLR CHHHHHHHHCCHHCC	35.49	22790023
142	Acetylation	NAAEITDKLGLHSLR CHHHHHHHHCCHHCC	35.49	23236377
147	Phosphorylation	TDKLGLHSLRHRNWY HHHHCCHHCCCCCEE	31.94	22942356

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ARF3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ARF3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ARF3_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ARF3_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.