dbPTM

ARC2A_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ARC2A_ARATH
UniProt AC	Q8LGI3
Protein Name	Actin-related protein 2/3 complex subunit 2A
Gene Name	ARPC2A
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	318
Subcellular Localization	Cytoplasm, cytoskeleton. Cell projection.
Protein Description	Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development..
Protein Sequence	MILLQSHSRFLLQTLLTRAQNLDKAVELDYQWIEFDDVRYHVQVTMKNPNLLLLSVSLPNPPPEAMSFDGLPLGAIEAIKTTYGTGFQILDPPRDGFSLTLKLNFSKVRPDEELLTKLASIREVVMGAPLKIIFKHLASRTVAPELDRLVAIMHRPNETFFLVPQADKVTVAFPMRFKDSVDTILATSFLKEFVEARRAAALNTAPSCSWSPTAPQELEGAPKETLSANAGFVTFVIFPRHVEGKKLDRTVWNLSTFHAYVSYHVKFSEGFMHTRMRRRVESMIQALDQAKPLEKTRSMNNKSFKRLGLNEVNHTNSK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of ARC2A_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ARC2A_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ARC2A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ARC2A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
ARPC4_ARATH	ARPC4	physical	17267444
SCAR3_ARATH	WAVE2	physical	17267444

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ARC2A_ARATH

Related Literatures of Post-Translational Modification