ARC1A_MOUSE - dbPTM
ARC1A_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ARC1A_MOUSE
UniProt AC Q9R0Q6
Protein Name Actin-related protein 2/3 complex subunit 1A
Gene Name Arpc1a
Organism Mus musculus (Mouse).
Sequence Length 370
Subcellular Localization Cytoplasm, cytoskeleton .
Protein Description Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks..
Protein Sequence MSLHQFLLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWTKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQKDGIWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVDEKPASTPWGSKMPFGQLMSEFGGSGTGGWVHGVSFSASGNRLAWVSHDSTVSVADASKSVQVSTLRTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDVPKQSIQRNMSAMERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKTLESSIQGLRIM
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSLHQFLLE
------CCHHHHHHC		34.2620415495
13S-palmitoylationFLLEPITCHAWNRDR
HHHCCCEEEEECCCC		1.8228680068
36AcetylationNHEVHIYKKNGSQWT
CCEEEEEEECCCCCE		38.8815618655
87UbiquitinationSQKDGIWKPTLVILR
ECCCCCCCCEEEEEE		26.6322790023
165AcetylationAAGSCDFKCRVFSAY
EECCCCCEEEEEEEE		14.1030985467
174AcetylationRVFSAYIKEVDEKPA
EEEEEEEEECCCCCC		38.7223954790
174MalonylationRVFSAYIKEVDEKPA
EEEEEEEEECCCCCC		38.7226073543
179AcetylationYIKEVDEKPASTPWG
EEEECCCCCCCCCCC		41.2323201123
179MalonylationYIKEVDEKPASTPWG
EEEECCCCCCCCCCC		41.2326320211
179UbiquitinationYIKEVDEKPASTPWG
EEEECCCCCCCCCCC		41.2327667366
182PhosphorylationEVDEKPASTPWGSKM
ECCCCCCCCCCCCCC		43.4629472430
183PhosphorylationVDEKPASTPWGSKMP
CCCCCCCCCCCCCCC		25.7629472430
187PhosphorylationPASTPWGSKMPFGQL
CCCCCCCCCCCHHHH		23.1629899451
235UbiquitinationVSVADASKSVQVSTL
CCHHHHCCCEEEEEC		57.2622790023
236PhosphorylationSVADASKSVQVSTLR
CHHHHCCCEEEEECC		18.4522817900
290UbiquitinationVSKLDVPKQSIQRNM
EECCCCCHHHHHHCH		57.4322790023
298PhosphorylationQSIQRNMSAMERFRN
HHHHHCHHHHHHHHC		28.1922324799
353PhosphorylationTGIDGAMTIWDFKTL
CCCCCCEEEEHHHHH		20.55-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ARC1A_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ARC1A_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ARC1A_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ARC1A_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ARC1A_MOUSE

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory