APT_MOUSE - dbPTM
APT_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID APT_MOUSE
UniProt AC P08030
Protein Name Adenine phosphoribosyltransferase
Gene Name Aprt
Organism Mus musculus (Mouse).
Sequence Length 180
Subcellular Localization Cytoplasm.
Protein Description Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis..
Protein Sequence MSEPELKLVARRIRSFPDFPIPGVLFRDISPLLKDPDSFRASIRLLASHLKSTHSGKIDYIAGLDSRGFLFGPSLAQELGVGCVLIRKQGKLPGPTVSASYSLEYGKAELEIQKDALEPGQRVVIVDDLLATGGTMFAACDLLHQLRAEVVECVSLVELTSLKGRERLGPIPFFSLLQYD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSEPELKLV
------CCHHHHHHH		62.9619854140
2Acetylation------MSEPELKLV
------CCHHHHHHH		62.96-
7Malonylation-MSEPELKLVARRIR
-CCHHHHHHHHHHHH		38.9726320211
7Acetylation-MSEPELKLVARRIR
-CCHHHHHHHHHHHH		38.9722826441
15PhosphorylationLVARRIRSFPDFPIP
HHHHHHHCCCCCCCC		8.3226824392
30PhosphorylationGVLFRDISPLLKDPD
CEEEECCHHHHCCHH		17.4921743459
34UbiquitinationRDISPLLKDPDSFRA
ECCHHHHCCHHHHHH		74.9322790023
34UbiquitinationRDISPLLKDPDSFRA
ECCHHHHCCHHHHHH		74.9322790023
34AcetylationRDISPLLKDPDSFRA
ECCHHHHCCHHHHHH		74.9323806337
51AcetylationRLLASHLKSTHSGKI
HHHHHHHHCCCCCCC		48.1322826441
57UbiquitinationLKSTHSGKIDYIAGL
HHCCCCCCCCEEEEE		35.1022790023
57AcetylationLKSTHSGKIDYIAGL
HHCCCCCCCCEEEEE		35.1022826441
57UbiquitinationLKSTHSGKIDYIAGL
HHCCCCCCCCEEEEE		35.1022790023
60PhosphorylationTHSGKIDYIAGLDSR
CCCCCCCEEEEECCC		8.99-
66PhosphorylationDYIAGLDSRGFLFGP
CEEEEECCCCCCCCH		39.0727180971
107UbiquitinationSYSLEYGKAELEIQK
EEEECCCEEEEEEEH		37.47-
114AcetylationKAELEIQKDALEPGQ
EEEEEEEHHHCCCCC		51.1023236377
135PhosphorylationDLLATGGTMFAACDL
EHHCCCHHHHHHHHH		15.51-
140GlutathionylationGGTMFAACDLLHQLR
CHHHHHHHHHHHHHH		3.2124333276
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of APT_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of APT_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of APT_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of APT_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of APT_MOUSE

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Related Literatures of Post-Translational Modification

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