APOA2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: APOA2_MOUSE
• UniProt AC: P09813
• Protein Name: Apolipoprotein A-II
• Gene Name: Apoa2
• Organism: Mus musculus (Mouse).
• Sequence Length: 102
• Subcellular Localization: Secreted .
• Protein Description: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism..
• Protein Sequence: MKLLAMVALLVTICSLEGALVKRQADGPDMQSLFTQYFQSMTDYGKDLMEKAKTSEIQSQAKAYFEKTHEQLTPLVRSAGTSLVNFFSSLMNLEEKPAPAAK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
24	Pyrrolidone_carboxylic_acid	EGALVKRQADGPDMQ HHHHHHHCCCCCCHH	37.78	-
49	Methionine sulfoxide	TDYGKDLMEKAKTSE HHHHHHHHHHHHHHH	11.55	-
49	Oxidation	TDYGKDLMEKAKTSE HHHHHHHHHHHHHHH	11.55	-
51	Ubiquitination	YGKDLMEKAKTSEIQ HHHHHHHHHHHHHHH	47.94	22790023
51	Ubiquitination	YGKDLMEKAKTSEIQ HHHHHHHHHHHHHHH	47.94	22790023
53	Ubiquitination	KDLMEKAKTSEIQSQ HHHHHHHHHHHHHHH	64.75	27667366
59	Phosphorylation	AKTSEIQSQAKAYFE HHHHHHHHHHHHHHH	42.47	24719451
62	Ubiquitination	SEIQSQAKAYFEKTH HHHHHHHHHHHHHHH	29.72	-
62	Ubiquitination	SEIQSQAKAYFEKTH HHHHHHHHHHHHHHH	29.72	22790023
62	Succinylation	SEIQSQAKAYFEKTH HHHHHHHHHHHHHHH	29.72	23954790
67	Acetylation	QAKAYFEKTHEQLTP HHHHHHHHHHHHHHH	45.33	21728379
67	Ubiquitination	QAKAYFEKTHEQLTP HHHHHHHHHHHHHHH	45.33	22790023
67	Ubiquitination	QAKAYFEKTHEQLTP HHHHHHHHHHHHHHH	45.33	22790023
73	Phosphorylation	EKTHEQLTPLVRSAG HHHHHHHHHHHHHHC	17.80	24719451
81	Phosphorylation	PLVRSAGTSLVNFFS HHHHHHCHHHHHHHH	20.71	25338131
82	Phosphorylation	LVRSAGTSLVNFFSS HHHHHCHHHHHHHHH	29.42	25338131
88	Phosphorylation	TSLVNFFSSLMNLEE HHHHHHHHHHCCCCC	20.58	25338131
89	Phosphorylation	SLVNFFSSLMNLEEK HHHHHHHHHCCCCCC	26.87	25338131
96	Ubiquitination	SLMNLEEKPAPAAK- HHCCCCCCCCCCCC-	36.78	22790023
96	Ubiquitination	SLMNLEEKPAPAAK- HHCCCCCCCCCCCC-	36.78	22790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of APOA2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of APOA2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of APOA2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of APOA2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.