APBLC_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: APBLC_ARATH
• UniProt AC: O81742
• Protein Name: Beta-adaptin-like protein C
• Gene Name: BETAC-AD
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 893
• Subcellular Localization: Golgi apparatus. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Associated with the trans-Golgi network. Component of the coat surrounding the cytoplasmic fa
• Protein Description: Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity)..
• Protein Sequence: MSGHDSKYFSTTKKGEIPELKEELNSQYKDKRKDAVKKVIAAMTVGKDVSSLFTDVVNCMQTENLELKKLVYLYLINYAKSQPDLAILAVNTFVKDSQDPNPLIRALAVRTMGCIRVDKITEYLCDPLQKCLKDDDPYVRKTAAICVAKLFDINAELVEDRGFLEALKDLISDNNPMVVANAVAALAEIQENSTSPIFEINSTILTKLLTALNECTEWGQVFILDALSRYKASDPREAENIVERVTPRLQHANCAVVLSAVKMILQQMELITSTDVIRNLCKKMAPPLVTLLSAEPEIQYVALRNINLIVQKRPTILAHEIKVFFCKYNDPIYVKMEKLEIMIKLASDRNIDQVLLEFKEYATEVDVDFVRKAVRAIGRCAIKLERAAERCISVLLELIKIKVNYVVQEAIIVIKDIFRRYPNTYESIIATLCESLDTLDEPEAKASMIWIIGEYAERIDNADELLESFLENFPEEPAQVQLQLLTATVKLFLKKPTEGPQQMIQVVLNNATVETDNPDLRDRAYIYWRLLSTDPEAAKDVVLAEKPVITDDSNQLDPSLLDELLANISTLSSVYHKPPEAFVTRLKTTVQKTEDEDYVEGSETGYPEASGNPVDGAASPSATTGYVTKLAAAPAPVPDLLGDLMGSDNAAIVPVDEPTTPSGRPLPVVLPASKGQGLQISAQLTRQDGQVFYSMLLENNSQSLLDGFMIQFNKNSFGLAAVGSLQVPPLQPGASARTMMPMVLSQNMSTGSTSSVLQVAVKNNQQPVWYFEDKIVLNALFSEDGRMERGTFLETWKSLPDSNEVQKEFPGITITSVESTLDLLAASNMFFIAKRKNGNQDVLYLSAKVPRGIPFLIELTAIVGQPGLKCAVKTPTPEIAPLFFEAVEILFKA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MSGHDSKYFSTTK --CCCCCCCCCCCCC	24.47	25561503
588	Phosphorylation	AFVTRLKTTVQKTED HHHHHHHEEEECCCC	36.47	25368622
589	Phosphorylation	FVTRLKTTVQKTEDE HHHHHHEEEECCCCC	21.25	25368622
593	Phosphorylation	LKTTVQKTEDEDYVE HHEEEECCCCCCCCC	31.42	25368622
598	Phosphorylation	QKTEDEDYVEGSETG ECCCCCCCCCCCCCC	9.80	25368622
602	Phosphorylation	DEDYVEGSETGYPEA CCCCCCCCCCCCCCC	20.62	23776212
604	Phosphorylation	DYVEGSETGYPEASG CCCCCCCCCCCCCCC	43.65	23776212
606	Phosphorylation	VEGSETGYPEASGNP CCCCCCCCCCCCCCC	12.81	23776212
610	Phosphorylation	ETGYPEASGNPVDGA CCCCCCCCCCCCCCC	37.12	23776212
619	Phosphorylation	NPVDGAASPSATTGY CCCCCCCCCCCCCCC	20.89	23776212
621	Phosphorylation	VDGAASPSATTGYVT CCCCCCCCCCCCCCC	35.43	23776212
623	Phosphorylation	GAASPSATTGYVTKL CCCCCCCCCCCCCHH	25.70	23776212
624	Phosphorylation	AASPSATTGYVTKLA CCCCCCCCCCCCHHH	26.65	23776212
626	Phosphorylation	SPSATTGYVTKLAAA CCCCCCCCCCHHHCC	11.67	23776212
628	Phosphorylation	SATTGYVTKLAAAPA CCCCCCCCHHHCCCC	16.32	23776212
724	Phosphorylation	FGLAAVGSLQVPPLQ CEEEEEEEEECCCCC	14.72	28011693

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of APBLC_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of APBLC_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of APBLC_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of APBLC_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.