AP4E_ARATH - dbPTM
AP4E_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID AP4E_ARATH
UniProt AC Q8L7A9
Protein Name AP-4 complex subunit epsilon
Gene Name At1g31730
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 938
Subcellular Localization Golgi apparatus, trans-Golgi network. Membrane, coated pit. Associated with the trans-Golgi network..
Protein Description Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system..
Protein Sequence MEQLKTIGRELAMGSQGGFGQSKEFLDLVKSIGEARSKAEEDRIVLSEVDILKRRLLEPDIPKRKMKEYIIRLVYIEMLGHDASFGYIYAVKMTHDDNLLLKRTGYLAVTLFLNEDHDLIILIVNTIQKDLRSDNYLVVCAALNAICRLINEETIPAVLPQVVELLNHQKEAVRKKAIMALHRFHRKSPSSVSHLVSNFRKRLCDNDPGVMGATLCPLFDLISEDVNSYKDLVSSFVSILKQVTERRLPKSYDYHQMPAPFIQIKLLKIMALLGSGDKNASDIMSMVLGDLFRKCDSSTNIGNAILYECIRCISCILPNPKLLEAAADAISKFLKSDSHNLKYMGIDGLGRLIKISPDIAEQHQLAVIDCLEDPDDTLKRKTFELLYKMTKSSNVEVIVDRMIDYMISINDNHYKTEIASRCVELAEQFAPSNQWFIQIMNKVFEHAGDLVNIKVAHNLMRLIAEGFGEDDDDADSKLRLSAVESYLQLISEPKLPSLFLQVISWVLGEYGTADGKYSASYISGKLCDVADAYSSDETVKGYAVSALMKIYAFEIASGRKVDVLPECQSLIEELLASHSTDLQQRAYELQALLALDARAVETILPLDASCEDIEVDKDLSFLNGYIQQAIESGAQPYISERERSGMFETTDYHPQDHHEVPTHALRFEAYELPKPSVPPQASNELVPVPEPSYYSESHQPISTSLVSERESSEIKLRLDGVKQKWGRPSYQSTTAASSTTPQAANGISTHSDAGVGSSSSKPRSSYEPKKPEIDPEKQRLAASLFGGSSSRTDKRSSSGGHKPAKGTANKTATVPKENQTPVQPPPDLLDFGEPTATTATAMDPFKELEGLMDSSSQDGGSSDVMGLYSDAAPVTTTTSVDSLLSELSDSSKGNSRTYQPQTSKGPNTKEALEKDALVRQMGVNPTSQNPTLFKDLLG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
15PhosphorylationGRELAMGSQGGFGQS
CHHHHCCCCCCCCCC
16.7425561503
47PhosphorylationEEDRIVLSEVDILKR
HHHCCEEEHHHHHHH
25.3619880383
783PhosphorylationEKQRLAASLFGGSSS
HHHHHHHHHHCCCCC
20.7223776212
788PhosphorylationAASLFGGSSSRTDKR
HHHHHCCCCCCCCCC
26.0623776212
789PhosphorylationASLFGGSSSRTDKRS
HHHHCCCCCCCCCCC
27.4123776212
790PhosphorylationSLFGGSSSRTDKRSS
HHHCCCCCCCCCCCC
40.6823776212
792PhosphorylationFGGSSSRTDKRSSSG
HCCCCCCCCCCCCCC
48.0619880383
897PhosphorylationSSKGNSRTYQPQTSK
CCCCCCCCCCCCCCC
26.7423776212
898PhosphorylationSKGNSRTYQPQTSKG
CCCCCCCCCCCCCCC
19.6523776212
902PhosphorylationSRTYQPQTSKGPNTK
CCCCCCCCCCCCCHH
38.8023776212
903PhosphorylationRTYQPQTSKGPNTKE
CCCCCCCCCCCCHHH
30.3023776212
908PhosphorylationQTSKGPNTKEALEKD
CCCCCCCHHHHHHHH
33.1423776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of AP4E_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of AP4E_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of AP4E_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of AP4E_ARATH !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of AP4E_ARATH

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Related Literatures of Post-Translational Modification

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