AP3D_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AP3D_SCHPO
• UniProt AC: Q9UTL8
• Protein Name: AP-3 complex subunit delta
• Gene Name: apl5
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 825
• Subcellular Localization: Golgi apparatus . Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
• Protein Description: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole (By similarity)..
• Protein Sequence: MVFERTLIDLIKGIRSHANDEEAFIATCLLECRKEATSQDADLKSEAILKLAYLEMLGVDISWASFQIVEVMSSSKILQKQKGYLAAVQSFKPDTDVLMLTTNLLKKDLMSSKVPEITLAIDGLSHFSTLGLARDLYRDVLILLNHSVPYVRKRTILLLYRLCLQYPEAISACIPKLRERLDDPDTSVVNAAVSVICELARRAPKNYLEFAPDLFHLLTTSSNNWMLIKLIKLFASLTPYEPRLVKKLIPSLTDIIENTHAMSLLYECINTIVSGNMLVGHSQCDKLASLCASKLRGFFEDTDQNLKYIALLCLRKLANTHPSLVSAQLDIILKCLVDTDTSIRLRALDLVNEIVNKENIRTIVKTLMLQLIVSSDESAVEDIRNSTATRIIEMTSKSTYMNIADFEWLLTVYVDLANIPGIDTGTLLNNQIIDLCVRVKALRPFSVDIFSQAILDPSYVSTTDCSVSEKRTDILPAIIWCLGEYAEFIEEYLDILDALTRPSFKKCSNLAHRLLLQAITKIFCQWCLEEEPTWGVEKFGLVKLWVEKIVSFIEQFLNFQDMEIQRRASEFYILFNQVSDIVNTSDTMEVLELQKKPPYIVQNTMYKLFFGEPLNPVAVKAQRKVMPDENLDLNCPINGVIEVPKELLENIIQSDDSLINFDTEVPSSGIDTFSKKQFNSLESVPVQRDLSSPFYLSSNQHTTTTNSEPENLNVETSMSDEAFNADKVTKVTKNKRRRKIFTSPSLQAMVVAQDEVPEGISLADIENKENPSNSNVYSLISLDPPLSTNQGSMGDIVLETKSPIRVEKKKSKKKKKKKEKTSGKE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
742	Phosphorylation	KRRRKIFTSPSLQAM CHHCCCCCCHHHHHH	43.11	29996109
743	Phosphorylation	RRRKIFTSPSLQAMV HHCCCCCCHHHHHHE	11.18	29996109
745	Phosphorylation	RKIFTSPSLQAMVVA CCCCCCHHHHHHEEE	32.64	29996109
802	Phosphorylation	DIVLETKSPIRVEKK CEEEECCCCCCCCCC	32.74	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AP3D_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AP3D_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AP3D_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of AP3D_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.