ANXD2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ANXD2_ARATH
• UniProt AC: Q9XEE2
• Protein Name: Annexin D2
• Gene Name: ANN2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 317
• Subcellular Localization: Cytoplasm, cytosol. Membrane. translocate from cytosol to membrane in a calcium-dependent manner.
• Protein Description: May mediate regulated, targeted secretion of Golgi-derived vesicles during seedling development..
• Protein Sequence: MASLKVPSNVPLPEDDAEQLHKAFSGWGTNEKLIISILAHRNAAQRSLIRSVYAATYNEDLLKALDKELSSDFERAVMLWTLDPPERDAYLAKESTKMFTKNNWVLVEIACTRPALELIKVKQAYQARYKKSIEEDVAQHTSGDLRKLLLPLVSTFRYEGDDVNMMLARSEAKILHEKVSEKSYSDDDFIRILTTRSKAQLGATLNHYNNEYGNAINKNLKEESDDNDYMKLLRAVITCLTYPEKHFEKVLRLSINKMGTDEWGLTRVVTTRTEVDMERIKEEYQRRNSIPLDRAIAKDTSGDYEDMLVALLGHGDA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MASLKVPSN ------CCCCCCCCC	24.46	-
8	Phosphorylation	MASLKVPSNVPLPED CCCCCCCCCCCCCCC	54.14	30407730
95	Phosphorylation	DAYLAKESTKMFTKN HHHHHHHHHCCCCCC	32.40	26452715
100	Phosphorylation	KESTKMFTKNNWVLV HHHHCCCCCCCEEEE	29.39	26452715
112	Phosphorylation	VLVEIACTRPALELI EEEEEEECCHHHHHH	30.57	-
129	Phosphorylation	KQAYQARYKKSIEED HHHHHHHHHHCHHHH	26.28	26452715
230	Sulfoxidation	ESDDNDYMKLLRAVI CCCCCHHHHHHHHHH	2.48	23289948
277	Sulfoxidation	TTRTEVDMERIKEEY ECCCHHCHHHHHHHH	4.50	23289948
284	Phosphorylation	MERIKEEYQRRNSIP HHHHHHHHHHHCCCC	14.38	-
289	Phosphorylation	EEYQRRNSIPLDRAI HHHHHHCCCCCCHHH	24.62	30407730
300	Phosphorylation	DRAIAKDTSGDYEDM CHHHHHCCCCCHHHH	33.62	23776212
301	Phosphorylation	RAIAKDTSGDYEDML HHHHHCCCCCHHHHH	39.54	23776212
304	Phosphorylation	AKDTSGDYEDMLVAL HHCCCCCHHHHHHHH	19.84	23776212
307	Sulfoxidation	TSGDYEDMLVALLGH CCCCHHHHHHHHHCC	1.85	23289948

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ANXD2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ANXD2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ANXD2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CDPK1_ARATH	CPK1	physical	22737156

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.