| UniProt ID | ANTR1_MOUSE | |
|---|---|---|
| UniProt AC | Q9CZ52 | |
| Protein Name | Anthrax toxin receptor 1 | |
| Gene Name | Antxr1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 562 | |
| Subcellular Localization |
Cell membrane Single-pass type I membrane protein. Cell projection, lamellipodium membrane Single-pass type I membrane protein. Cell projection, filopodium membrane Single-pass type I membrane protein. At the membrane of lamellipodia and at the ti |
|
| Protein Description | Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells (By similarity).. | |
| Protein Sequence | MDRAGRLGAGLRGLCVAALVLVCAGHGGRREDGGPACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHRFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENSQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINDSVTLNEKPFAVEDTYLLCPAPILKEVGMKAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLVLFLLLALALLWWFWPLCCTVIIKEVPPPPVEESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRVKNSQPAKYPLNNTYHPSSPPPAPIYTPPPPAPHCPPPAPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRPSV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 79 | Phosphorylation | ISPQLRMSFIVFSTR CCHHHCCEEEEEECC | 12.85 | 20047950 | |
| 88 | Phosphorylation | IVFSTRGTTLMKLTE EEEECCCCEEEHHHH | 17.29 | 21183079 | |
| 89 | Phosphorylation | VFSTRGTTLMKLTED EEECCCCEEEHHHHC | 27.90 | 21183079 | |
| 164 | N-linked_Glycosylation | FYSEREANRSRDLGA ECCHHHHHHCCCCEE | 37.39 | - | |
| 182 | N-linked_Glycosylation | CVGVKDFNETQLARI EEECCCCCHHHHHHH | 62.63 | - | |
| 260 | N-linked_Glycosylation | VLCSFKINDSVTLNE EEEEEEECCCCCCCC | 35.77 | - | |
| 360 | Phosphorylation | PPPPVEESEEEDDDG CCCCCCCCCCCCCCC | 36.48 | 26824392 | |
| 375 | Phosphorylation | LPKKKWPTVDASYYG CCCCCCCCCCCHHCC | 29.87 | 29514104 | |
| 379 | Phosphorylation | KWPTVDASYYGGRGV CCCCCCCHHCCCCCC | 17.90 | 29514104 | |
| 380 | Phosphorylation | WPTVDASYYGGRGVG CCCCCCHHCCCCCCC | 14.09 | 26032504 | |
| 381 | Phosphorylation | PTVDASYYGGRGVGG CCCCCHHCCCCCCCC | 15.60 | 26032504 | |
| 412 | Acetylation | GAKLEKAKNARVKMP HHHHHHHHHCCCCCC | 63.31 | 15606833 | |
| 423 | Phosphorylation | VKMPEQEYEFPEPRN CCCCHHHCCCCCCCC | 23.67 | 26032504 | |
| 554 | Phosphorylation | PNRAPPPSRPPPRPS CCCCCCCCCCCCCCC | 64.29 | 22324799 | |
| 561 | Phosphorylation | SRPPPRPSV------ CCCCCCCCC------ | 41.56 | 54887303 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ANTR1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ANTR1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ANTR1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of ANTR1_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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