ANS1B_MOUSE - dbPTM
ANS1B_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ANS1B_MOUSE
UniProt AC Q8BIZ1
Protein Name Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Gene Name Anks1b
Organism Mus musculus (Mouse).
Sequence Length 1259
Subcellular Localization Cytoplasm.
Isoform 2: Nucleus.
Isoform 4: Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendritic spine. Nucleus.
Protein Description Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells..
Protein Sequence MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMIISAHPNLMSCNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHEAALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHPSQKSLQIATLLQDYLEGAGRSAAVLEEHAQEDTAQETHLSSPAESPQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHTISDHYLDNLSKISEEELGKNGSQSVRTSSTINLSPGEVEDEEEDPNSCGPTGLWEALTPCNGCRNLGFPMLAQESYPKKRNFPMEMEPSASLDTFPSENENFLCELVDTAVTKKPCSLEIARAPSPRTDNASEVAITAPGTSHHRNSSTGPTPDCSPPSPDTALKNIVKVIRPQPKQRTSIVSSLDFQRMNHNQEYFEISTSTGCTSFTSSPAASPPTSSVETTEVKNEGAEHADDLSQQEDDEPPKEYDAGQFAGLLHGSSPACESPENPFHLYGKRNTCEDGPDEASLANSPLPFKQTPIENNPEPSVKKVKPKVVSRTIFHKRNHQLENHTIVGTRMSRSGSRNGDQWGVNPGGFVERACTLGRIRSLPKALIDMHLSKNVSKSDSDLIAYPSKDKARVNWSKSSTAERSSKDNSERTPSFTSEWEEIDKIMNSIDVGINSELEGMNGETTRPRCPVQTVGQWLESIGLPQYENHLMANGFDSVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWELELINVLKISLIGHRKRILASLGDRLHDDPPQKPPRSITLREPSGNHTPPQLSPSLSQSTYTTGGSLDVPHIIMQGDARRRRNENYFDDIPRSKLERQMAQTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCRKSTEQMKKVPTIILSVSYKGVKFIDAANKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVQIDPSEQKTLANLPWIVEPGQEAKRGINTKYETTIF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
15 (in isoform 4)Phosphorylation-18.4429899451
15 (in isoform 2)Phosphorylation-18.4429899451
20 (in isoform 4)Phosphorylation-38.5529899451
20 (in isoform 2)Phosphorylation-38.5529899451
21 (in isoform 4)Phosphorylation-47.4526804993
21 (in isoform 2)Phosphorylation-47.4526804993
93PhosphorylationNVADNKGYFPIHLAA
CCCCCCCCCCEEEEE		14.0622807455
163PhosphorylationIRNSKLETPLDLAAL
CCCCCCCCHHHHHHH		39.3225159016
196PhosphorylationSCNTRKHTPLHLAAR
CCCCCCCCCCHHHHH		30.49-
303PhosphorylationEEHAQEDTAQETHLS
HHHHCCCCHHHHCCC		29.5029899451
307PhosphorylationQEDTAQETHLSSPAE
CCCCHHHHCCCCCCC		18.9429899451
310PhosphorylationTAQETHLSSPAESPQ
CHHHHCCCCCCCCCC		27.0322817900
311PhosphorylationAQETHLSSPAESPQK
HHHHCCCCCCCCCCC		34.1922817900
315PhosphorylationHLSSPAESPQKTKSE
CCCCCCCCCCCCCCC		34.4422817900
343PhosphorylationKLCQEKDYSFEDLCH
HHHHHCCCCHHHHHH		26.7429899451
344PhosphorylationLCQEKDYSFEDLCHT
HHHHCCCCHHHHHHH		32.0929899451
351PhosphorylationSFEDLCHTISDHYLD
CHHHHHHHHHHHHHH		22.6029899451
353PhosphorylationEDLCHTISDHYLDNL
HHHHHHHHHHHHHHH		21.3525521595
356PhosphorylationCHTISDHYLDNLSKI
HHHHHHHHHHHHHHC		22.2722807455
364PhosphorylationLDNLSKISEEELGKN
HHHHHHCCHHHHCCC		42.5725521595
397 (in isoform 3)Phosphorylation-63.3529899451
503PhosphorylationRNSSTGPTPDCSPPS
CCCCCCCCCCCCCCC		32.8624925903
507PhosphorylationTGPTPDCSPPSPDTA
CCCCCCCCCCCHHHH		47.4224925903
510PhosphorylationTPDCSPPSPDTALKN
CCCCCCCCHHHHHHH		38.5025521595
513PhosphorylationCSPPSPDTALKNIVK
CCCCCHHHHHHHHHH		36.9624925903
530PhosphorylationRPQPKQRTSIVSSLD
CCCCCCCCCEEEECC		21.9519060867
531PhosphorylationPQPKQRTSIVSSLDF
CCCCCCCCEEEECCH		24.1519060867
589PhosphorylationAEHADDLSQQEDDEP
CCCHHHHHHCCCCCC		36.4929899451
600PhosphorylationDDEPPKEYDAGQFAG
CCCCCCCCCHHHHHH		19.7429899451
613PhosphorylationAGLLHGSSPACESPE
HHHHCCCCCCCCCCC		22.5529899451
618PhosphorylationGSSPACESPENPFHL
CCCCCCCCCCCCCCE		37.0829899451
631PhosphorylationHLYGKRNTCEDGPDE
CEECCCCCCCCCCCH		22.7029899451
651PhosphorylationSPLPFKQTPIENNPE
CCCCCCCCCCCCCCC		27.16103260583
696PhosphorylationTRMSRSGSRNGDQWG
EEECCCCCCCCCCCC		24.6629899451
715PhosphorylationGFVERACTLGRIRSL
HHHHHHHHHHHHHHH		31.1229899451
721PhosphorylationCTLGRIRSLPKALID
HHHHHHHHHHHHHHH		46.80101545567
736PhosphorylationMHLSKNVSKSDSDLI
HHHCCCCCCCHHCCE		35.5224925903
738PhosphorylationLSKNVSKSDSDLIAY
HCCCCCCCHHCCEEC		34.5425521595
740PhosphorylationKNVSKSDSDLIAYPS
CCCCCCHHCCEECCC		41.2125521595
745PhosphorylationSDSDLIAYPSKDKAR
CHHCCEECCCCCCCC		10.8824925903
769PhosphorylationERSSKDNSERTPSFT
CCCCCCCCCCCCCCC		38.2929899451
772PhosphorylationSKDNSERTPSFTSEW
CCCCCCCCCCCCHHH		21.1629899451
774PhosphorylationDNSERTPSFTSEWEE
CCCCCCCCCCHHHHH		40.3125521595
776PhosphorylationSERTPSFTSEWEEID
CCCCCCCCHHHHHHH		30.0326643407
777PhosphorylationERTPSFTSEWEEIDK
CCCCCCCHHHHHHHH		38.4126643407
900PhosphorylationDSIELGDYTKAFLIN
HHCCCCCCCEEEEEC		14.3518034455
953UbiquitinationLHDDPPQKPPRSITL
HCCCCCCCCCCCEEE		63.86-
964PhosphorylationSITLREPSGNHTPPQ
CEEEECCCCCCCCCC		47.6919060867
968PhosphorylationREPSGNHTPPQLSPS
ECCCCCCCCCCCCCC		40.4419060867
973PhosphorylationNHTPPQLSPSLSQST
CCCCCCCCCCCCCCC		13.7519060867
975PhosphorylationTPPQLSPSLSQSTYT
CCCCCCCCCCCCCEE		36.9620415495
977PhosphorylationPQLSPSLSQSTYTTG
CCCCCCCCCCCEECC		26.8222807455
980PhosphorylationSPSLSQSTYTTGGSL
CCCCCCCCEECCCCC		19.7622807455
981PhosphorylationPSLSQSTYTTGGSLD
CCCCCCCEECCCCCC		13.9321082442
983PhosphorylationLSQSTYTTGGSLDVP
CCCCCEECCCCCCCC		29.1829899451
986PhosphorylationSTYTTGGSLDVPHII
CCEECCCCCCCCEEE		23.8121183079
1006PhosphorylationRRRRNENYFDDIPRS
HHHCCCCCCCCCCHH		11.3816141072
1013PhosphorylationYFDDIPRSKLERQMA
CCCCCCHHHHHHHHH		35.9251458951
1029PhosphorylationTGDWGEPSITLRPPN
HCCCCCCCCEECCCC		24.73101545559
1031PhosphorylationDWGEPSITLRPPNEA
CCCCCCCEECCCCCC		22.50101545575
1072UbiquitinationYLGSMLIKELRGTES
HHHHHHHHHHHCCCC		46.8922790023
1077PhosphorylationLIKELRGTESTQDAC
HHHHHHCCCCHHHHH		21.9625521595
1114UbiquitinationSVSYKGVKFIDAANK
EEECCCCEEECCCCC		45.3222790023
1199PhosphorylationRKGGHSSTLPESFEN
HCCCCCCCCCHHHCC		49.7118850549
1222PhosphorylationPRVSIRKSVQIDPSE
CCEEEEECEECCHHH		14.9225521595
1231UbiquitinationQIDPSEQKTLANLPW
ECCHHHCCHHHCCCE		41.2622790023
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ANS1B_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ANS1B_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ANS1B_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ANS1B_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ANS1B_MOUSE

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Large-scale identification and evolution indexing of tyrosinephosphorylation sites from murine brain.";
Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.;
J. Proteome Res. 7:311-318(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-900, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory