ANR24_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ANR24_HUMAN
• UniProt AC: Q8TF21
• Protein Name: Ankyrin repeat domain-containing protein 24
• Gene Name: ANKRD24
• Organism: Homo sapiens (Human).
• Sequence Length: 1146
• Protein Sequence: MKTLRARFKKTELRLSPTDLGSCPPCGPCPIPKPAARGRRQSQDWGKSDERLLQAVENNDAPRVAALIARKGLVPTKLDPEGKSAFHLAAMRGAASCLEVMIAHGSNVMSADGAGYNALHLAAKYGHPQCLKQLLQASCVVDVVDSSGWTALHHAAAGGCLSCSEVLCSFKAHLNPQDRSGATPLIIAAQMCHTDLCRLLLQQGAAANDQDLQGRTALMLACEGASPETVEVLLQGGAQPGITDALGQDAAHYGALAGDKLILHLLQEAAQRPSPPSALTEDDSGEASSQNSMSSHGKQGAPKKRKAPPPPASIPMPDDRDAYEEIVRLRQERGRLLQKIRGLEQHKERRQQESPEASSLHILERQVQELQQLLVERQEEKESLGREVESLQSRLSLLENERENTSYDVTTLQDEEGELPDLPGAEVLLSRQLSPSAQEHLASLQEQVAVLTRQNQELMEKVQILENFEKDETQMEVEALAEVIPLALYDSLRAEFDQLRRQHAEALQALRQQETREVPREEGAACGESEVAGATATKNGPTHMELNGSVAPETKVNGAETIDEEAAGDETMEARTMEAEATGAEATGAEATGAKVTETKPTGAEVREMETTEEEANMETKPTGAQATDTETTGVEAMGVEATKTKAEEAEMQAYGVGAGQAEPPVTGTTNMEATGSRATGMESTGVSATGVENPGVEATVPGISAGPILHPGAAEASEKLQVELETRIRGLEEALRQREREAAAELEAALGKCEAAEAEAGRLRERVREAEGSGASGGGGGDTTQLRAALEQAREDLRDRDSRLRELEAASACLDEARASRLLAEEEARGLRAELAQREEARLEQSRELEVLREQLATARATGEQQRTAAAELGRARDAAEARVAELPAACEEARQGLAELREASEALRQSVVPASEHRRLQEEALELRGRAASLEQEVVATGKEAARLRAELERERVCSVALSEHERIVGTLQANVAQLEGQLEELGRRHEKTSAEVFQVQREALFMKSERHAAEAQLATAEQQLRGLRTEAERARQAQSRAQEALDKAKEKDKKITELSKEVFNLKEALKEQPAALATPEVEALRDQVKDLQQQLQEAARDHSSVVALYRSHLLYAIQGQMDEDVQRILSQILQMQRLQAQGR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
229	Phosphorylation	CEGASPETVEVLLQG HCCCCHHHHHHHHCC	25.92	46164067
243	Phosphorylation	GGAQPGITDALGQDA CCCCCCHHHHHCCCH	22.57	46164073
253	Phosphorylation	LGQDAAHYGALAGDK HCCCHHHHHHHHHHH	10.20	46164079
354	Phosphorylation	KERRQQESPEASSLH HHHHHHCCCCHHHHH	24.57	24076635
358	Phosphorylation	QQESPEASSLHILER HHCCCCHHHHHHHHH	31.60	22985185
383	Phosphorylation	ERQEEKESLGREVES HHHHHHHHHHHHHHH	47.38	29978859
393	Phosphorylation	REVESLQSRLSLLEN HHHHHHHHHHHHHHH	40.25	29978859
396	Phosphorylation	ESLQSRLSLLENERE HHHHHHHHHHHHHHC	29.78	23312004
434	Phosphorylation	VLLSRQLSPSAQEHL HHHHCCCCHHHHHHH	14.42	24076635
436	Phosphorylation	LSRQLSPSAQEHLAS HHCCCCHHHHHHHHH	38.93	25307156
443	Phosphorylation	SAQEHLASLQEQVAV HHHHHHHHHHHHHHH	36.62	26074081
452	Phosphorylation	QEQVAVLTRQNQELM HHHHHHHHHHHHHHH	24.49	26074081
576	Phosphorylation	DETMEARTMEAEATG CCCHHHHHHHHHHHC	26.81	18491316
582	Phosphorylation	RTMEAEATGAEATGA HHHHHHHHCCCCCCC	28.56	23532336
597	Phosphorylation	EATGAKVTETKPTGA CCCCCEEEECCCCCC	36.91	18491316
599	Phosphorylation	TGAKVTETKPTGAEV CCCEEEECCCCCCCC	32.72	18491316
620	Phosphorylation	EEEANMETKPTGAQA HHHHCCCCCCCCCCC	31.39	50565473
774	Phosphorylation	RVREAEGSGASGGGG HHHHHCCCCCCCCCC	23.77	68706217
777	Phosphorylation	EAEGSGASGGGGGDT HHCCCCCCCCCCCCH	41.31	68706221
784	Phosphorylation	SGGGGGDTTQLRAAL CCCCCCCHHHHHHHH	21.51	68706225
785	Phosphorylation	GGGGGDTTQLRAALE CCCCCCHHHHHHHHH	30.28	68706229
869	Phosphorylation	ATGEQQRTAAAELGR HHHHHHHHHHHHHHH	19.13	24505115
935	Phosphorylation	ELRGRAASLEQEVVA HHHHHHHHHHHHHHH	31.30	113329127
961	Phosphorylation	LERERVCSVALSEHE HHHHHHHHHHCCCCH	13.94	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ANR24_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ANR24_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ANR24_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EF1A1_HUMAN	EEF1A1	physical	16169070
LRIF1_HUMAN	LRIF1	physical	16169070
U119A_HUMAN	UNC119	physical	16169070

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.