dbPTM

ANP1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ANP1_SCHPO
UniProt AC	O74745
Protein Name	Mannan polymerase II complex anp1 subunit
Gene Name	anp1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	430
Subcellular Localization	Endoplasmic reticulum membrane Single-pass type II membrane protein . Golgi apparatus membrane Single-pass type II membrane protein . Cis-Golgi (PubMed:18184749). Recycles between endoplasmic reticulum and Golgi (By similarity).
Protein Description	The M-Pol II complex possesses alpha-1,6-mannosyltransferase activity and is probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins..
Protein Sequence	MKANRDFGRDGGPFSITPNRFQPKSSGNPIFRQKTIRTVGIIALTLVLFLFFHRSFFSSFGEFPSFSSTANAPNSDVQEYDLRKVMNAKFTGDYSPKEKVLICAPLRNAAEHLNMFFGHMNNLTYPHELIDLAFLISDTDDNTLEVLKQHLDAIQNDEDESKHFNNVLIMLKDFGAIFGQEFSDRHGFAAQGPRRKLMARARNWLLSAAIQPYHSWVYWRDVDVETAPNTILEDLMRHDKDIIVPNVYRPLPDWLGNEQPYDLNSWAESETALQLADTLGEDDVIVEGYAEYATWRPHLAYLRDPNGDPSVEMPLDGIGGVSIMSKAKVHLEGCEFPAFSFEKHAETEGFGKMAKRMGFSVYGLPHYVIWHIYEPSDDDKRIMAEMERERKEREAAELEEAKKYQTAGFTQPDDQGAEEGPLAHADDHVD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	GRDGGPFSITPNRFQ CCCCCCCCCCCCCCC	28.78	25720772
17	Phosphorylation	DGGPFSITPNRFQPK CCCCCCCCCCCCCCC	17.20	25720772
122	N-linked_Glycosylation	MFFGHMNNLTYPHEL HHHHCCCCCCCCHHH	26.62	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ANP1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ANP1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ANP1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ANP1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ANP1_SCHPO

Related Literatures of Post-Translational Modification