ANKAR_HUMAN - dbPTM
ANKAR_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ANKAR_HUMAN
UniProt AC Q7Z5J8
Protein Name Ankyrin and armadillo repeat-containing protein
Gene Name ANKAR
Organism Homo sapiens (Human).
Sequence Length 1434
Subcellular Localization Membrane
Single-pass membrane protein .
Protein Description
Protein Sequence MLRLPKKGLPRFEQVQDEDTYLENLAIQRNASAFFEKYDRSEIQELLTTALVSWLSAKEDVRSQVDLPCGIMSQMNNVGFSTAILLTPVDPTALLDYREVHQMIRELAIGIYCLNQIPSISLEANYDQSSSCQLPPAYYDTRIGQILINIDYMLKALWHGIYMPKEKRARFSELWRAIMDIDPDGKPQTNKDIFSEFSSAGLTDITKDPDFNEIYDEDVNEDPTYDPNSPEETAVFMKYAENIMLKLTFSTTQIQQYENVFIFETGYWLTNAIKYNQDYLDICTYQRLQQRLYLQKKIIQKHFEKKKDIRRGIGYLKLICFLIPFLLSLKKKMKVPYLSSLLQPFSDDKVKTERELPPFIYGRDFKCQNFHYKENQYFHVHGGIEFDISTPSIENALEDFQKNLEKIRDCAANTFIEDSGYKEYYSIPVMEFHGKSYYVIYFELETFYQQLYKTQWWGAINEIVNNLRLKRLPLTDAQLHEQFKKKLGFKRAMKCKSIPFGMKSAVERGLSAVFHTFSRKTSSSTINVSDEAGYTIFHHAALHNRVSIICQLCNANFKVNQRRFVTFSQGPTPLHLAAQACSLETTVCLLCSKADYTLSEKRGWMPIHFAAFYDNVCIIIALCRKDPSLLEAEATAENQCTPLLLAATSGALDTIQYLFSIGANWRKTDIKGNNIIHLSVLTFHTEVLKYIIKLNIPELPVWKTLVEMLQCESYKRRMMAVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVGLLSNISTHKSAVHALVEAGGIPSLINLLVCDEPEVHSRCAVILYDIAQCENKDVIAKYNGIPSLINLLNLNIENVLVNVMNCIRVLCIGNENNQRAVREHKGLPYLIRFLSSDSDVLKAVSSAAIAEVGRDNKEIQDAIAMEGAIPPLVALFKGKQISVQMKGAMAVESLASHNALIQKAFLEKSLTKYLLKLLKAFQIDVKEQGAVALWALAGQTLKQQKYMAEQIGYSFIINMLLSPSAKMQYVGGEAVIALSKDSRMHQNQICEGNGIAPLVRLLRISTIAEGTLLSVIRAVGSICIGVAHTSNPVSQQLVVDENAFPVLIQLLRNHPSPNIKVEVAFSLACIVLGNDVLQKDLHENEGFEYADVLYLLHSTEKDICLRAGYALTLFAFNNRFQQYLILESGIMTISIFERFLESTVETEKAMAAFQIVVLAKVIRDMDHITLSARGVTILVDSLYSVQTSTIVLTGNLIASLAHSRAGIPEAFTTLGTIQRLCYHLYSGIEEVRAACSSALGYLTYNANAFRILLKECRNKPNQFIRIKNNISRDASINPAFLKEFQMQQTLVGLPSLSLEKNGGPSIIPIFKRGKEHRRKLKPKIQPKDSLTLLPPVTNFMGLFKATKKTKDSHNIFSFSSTITSDITNVSRPRIVCLNQLGKHVQKANPEPAEG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
41PhosphorylationFFEKYDRSEIQELLT
HHHHCCHHHHHHHHH		35.8322210691
49PhosphorylationEIQELLTTALVSWLS
HHHHHHHHHHHHHHH		20.2622210691
56PhosphorylationTALVSWLSAKEDVRS
HHHHHHHHHCHHHHH		30.9122210691
250PhosphorylationIMLKLTFSTTQIQQY
HHHEEEEECHHHHEE		25.8818452278
265PhosphorylationENVFIFETGYWLTNA
EEEEEEECCHHHHHH		25.4818452278
293PhosphorylationQRLQQRLYLQKKIIQ
HHHHHHHHHHHHHHH		14.8518083107
328PhosphorylationFLIPFLLSLKKKMKV
HHHHHHHHHHHHCCC		40.0524719451
337PhosphorylationKKKMKVPYLSSLLQP
HHHCCCCHHHHHCCC		23.3928851738
340PhosphorylationMKVPYLSSLLQPFSD
CCCCHHHHHCCCCCC		30.4228851738
346PhosphorylationSSLLQPFSDDKVKTE
HHHCCCCCCCCCCCC		52.1328851738
414PhosphorylationIRDCAANTFIEDSGY
HHHHHHCCCCCCCCC		22.6630576142
421PhosphorylationTFIEDSGYKEYYSIP
CCCCCCCCCEEEEEE		12.4730576142
424PhosphorylationEDSGYKEYYSIPVME
CCCCCCEEEEEEEEE		9.8129759185
425PhosphorylationDSGYKEYYSIPVMEF
CCCCCEEEEEEEEEE		10.9529759185
596PhosphorylationLLCSKADYTLSEKRG
HHHCCCCEECCCCCC		17.9126074081
597PhosphorylationLCSKADYTLSEKRGW
HHCCCCEECCCCCCC		25.1026074081
599PhosphorylationSKADYTLSEKRGWMP
CCCCEECCCCCCCCC		33.0226074081
685PhosphorylationLSVLTFHTEVLKYII
EEEEEEHHHHHHHHH		24.4946163567
1019PhosphorylationGEAVIALSKDSRMHQ
CEEEEEECCCCCCHH		25.9568714879
1129PhosphorylationHENEGFEYADVLYLL
CCCCCCCHHHHHHHH		13.0730257219
1134PhosphorylationFEYADVLYLLHSTEK
CCHHHHHHHHHCCCC		13.6830257219
1216PhosphorylationTLSARGVTILVDSLY
EEEECCEEEEECCCC		16.0624043423
1221PhosphorylationGVTILVDSLYSVQTS
CEEEEECCCCCCCCC		23.0224043423
1223PhosphorylationTILVDSLYSVQTSTI
EEEECCCCCCCCCEE		15.6724043423
1224PhosphorylationILVDSLYSVQTSTIV
EEECCCCCCCCCEEE		17.0324043423
1227PhosphorylationDSLYSVQTSTIVLTG
CCCCCCCCCEEEEEC		26.1924043423
1228PhosphorylationSLYSVQTSTIVLTGN
CCCCCCCCEEEEECH		10.0724043423
1229PhosphorylationLYSVQTSTIVLTGNL
CCCCCCCEEEEECHH		20.6324043423
1233PhosphorylationQTSTIVLTGNLIASL
CCCEEEEECHHHHHH		17.0924043423
1239PhosphorylationLTGNLIASLAHSRAG
EECHHHHHHHHHHCC		21.0624043423
1243PhosphorylationLIASLAHSRAGIPEA
HHHHHHHHHCCCCHH		20.4424043423
1354AcetylationIPIFKRGKEHRRKLK
EECCCCCHHHHHHCC		55.147365133
1407PhosphorylationSTITSDITNVSRPRI
CEECCCCCCCCCCEE		34.2646163561
1410PhosphorylationTSDITNVSRPRIVCL
CCCCCCCCCCEEEEE		38.3446163555
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ANKAR_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ANKAR_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ANKAR_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ANKAR_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ANKAR_HUMAN

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Related Literatures of Post-Translational Modification

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