AN33B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AN33B_HUMAN
• UniProt AC: A6NCL7
• Protein Name: Ankyrin repeat domain-containing protein 33B
• Gene Name: ANKRD33B
• Organism: Homo sapiens (Human).
• Sequence Length: 494
• Protein Sequence: MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	CMTPPPPSPPRGAQV CCCCCCCCCCCCCCC	54.00	17081983
37	Phosphorylation	VEEDPADYEEFEDFS CCCCCCCHHHHCCHH	21.33	27642862
44	Phosphorylation	YEEFEDFSSLPDTRS HHHHCCHHCCCCCCC	43.20	26471730
45	Phosphorylation	EEFEDFSSLPDTRSI HHHCCHHCCCCCCCC	43.87	27642862
49	Phosphorylation	DFSSLPDTRSIASDD CHHCCCCCCCCCCCC	25.11	26471730
110	Phosphorylation	TLVRRGVSVEEAQET HHHHCCCCHHHHHHH	27.00	28674419
203	Phosphorylation	KAAMQGRTDCIRALM HHHHCCCHHHHHHHH	41.89	29083192
284	Phosphorylation	KNCLQRLTDCVLSVL CHHHHHHHHHHHHHH	29.55	23312004
289	Phosphorylation	RLTDCVLSVLTPRSV HHHHHHHHHHCCCCC	8.49	23312004
370	Methylation	GGAGQRGRTGQEDAD CCCCCCCCCCCCCCC	37.56	-
405	Phosphorylation	APAPRKASLLPLQRL CCCCCCCCCHHHHHH	33.21	27422710
416	Phosphorylation	LQRLRRRSVRPGVVV HHHHHHCCCCCCEEE	22.22	27422710
464	Acetylation	KWRYKEAKEEKRKAE CCHHHHHHHHHHHHH	68.45	7395505
467	Acetylation	YKEAKEEKRKAEEAE HHHHHHHHHHHHHHH	61.36	7395515

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AN33B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AN33B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AN33B_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of AN33B_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.