AN30A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AN30A_HUMAN
• UniProt AC: Q9BXX3
• Protein Name: Ankyrin repeat domain-containing protein 30A
• Gene Name: ANKRD30A
• Organism: Homo sapiens (Human).
• Sequence Length: 1397
• Protein Sequence: MEEISAAAVKVVPGPERPSPFSQLVYTSNDSYIVHSGDLRKIHKAASRGQVRKLEKMTKRKKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVEKTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPREITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKLKEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDACLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHFLERKMQHHLLKEKNEEIFNYNNHLKNRIYQYEKEKAETENS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MEEISAAAVKVVPG -CCCCCCCEEEECCC	13.14	18491316
63	Phosphorylation	KMTKRKKTINLNIQD HHHCCCCEEECCCCH	20.38	18491316
179	Phosphorylation	SLTPLLLSITKRSEQ CCHHHHHHHHCCCHH	28.34	24719451
181	Phosphorylation	TPLLLSITKRSEQIV HHHHHHHHCCCHHHH	19.61	46164171
215	Phosphorylation	ALMLAVCHGSSEIVG HHHHHHHCCCHHHHH	32.35	-
220	Phosphorylation	VCHGSSEIVGMLLQQ HHCCCHHHHHHHHHC	3.33	-
221	Phosphorylation	CHGSSEIVGMLLQQN HCCCHHHHHHHHHCC	3.02	-
271	Phosphorylation	LSKNHQNTNPEGTSA HHHHCCCCCCCCCCC	45.65	63769003
276	Phosphorylation	QNTNPEGTSAGTPDE CCCCCCCCCCCCCCC	17.47	50565497
277	Phosphorylation	NTNPEGTSAGTPDEA CCCCCCCCCCCCCCC	35.24	63769007
280	Phosphorylation	PEGTSAGTPDEAAPL CCCCCCCCCCCCCCH	27.55	50565501
319	Phosphorylation	RTPDTAESLVEKTPD CCCCHHHHHHHHCHH	34.94	26074081
324	Phosphorylation	AESLVEKTPDEAASL HHHHHHHCHHHHHHH	23.59	26074081
330	Phosphorylation	KTPDEAASLVEGTSD HCHHHHHHHHCCCCC	39.74	26074081
335	Phosphorylation	AASLVEGTSDKIQCL HHHHHCCCCCHHHHH	21.90	26074081
336	Phosphorylation	ASLVEGTSDKIQCLE HHHHCCCCCHHHHHH	48.00	26074081
346	Phosphorylation	IQCLEKATSGKFEQS HHHHHHHHCCCCCCC	49.43	20860994
349	Ubiquitination	LEKATSGKFEQSAEE HHHHHCCCCCCCCCC	45.56	-
422	Acetylation	RKIAWEKKETPVKTG CEEEEECCCCCCCCC	56.13	30586929
427	Acetylation	EKKETPVKTGCVARV ECCCCCCCCCCEEEE	40.16	30586933
428	Phosphorylation	KKETPVKTGCVARVT CCCCCCCCCCEEEEC	35.73	22286973
435	Phosphorylation	TGCVARVTSNKTKVL CCCEEEECCCCCEEH	22.49	27251275
436	Phosphorylation	GCVARVTSNKTKVLE CCEEEECCCCCEEHH	33.21	22286979
439	O-linked_Glycosylation	ARVTSNKTKVLEKGR EEECCCCCEEHHCCC	30.54	30379171
439	Phosphorylation	ARVTSNKTKVLEKGR EEECCCCCEEHHCCC	30.54	22286985
490	Phosphorylation	DSRSLFESSAKIQVC CCHHHHHHCCEEEEE	28.41	27251275
491	Phosphorylation	SRSLFESSAKIQVCI CHHHHHHCCEEEEEC	26.78	27251275
520	Phosphorylation	VEEPPKKPSAFKPAI CCCCCCCCCCCCCCH	36.70	-
576	Phosphorylation	ESLCETVSQKDVCLP HHHHHHHCCCCCCCC	38.64	113334323
617	Phosphorylation	ATCGMKVSIPTKALE HHHCCEEECCCCCEE	19.82	22817900
620	Phosphorylation	GMKVSIPTKALELKD CCEEECCCCCEECCC	27.55	23612710
639	Phosphorylation	KAEPPGKPSAFEPAT CCCCCCCCCCCCCCC	36.48	-
640	Phosphorylation	AEPPGKPSAFEPATE CCCCCCCCCCCCCCH	49.42	22210691
646	Phosphorylation	PSAFEPATEMQKSVP CCCCCCCCHHHHCCC	42.58	22210691
664	Phosphorylation	LELKNEQTLRADEIL HHHCCCHHCCHHHCC	16.42	24719451
678	Ubiquitination	LPSESKQKDYEENSW CCCHHHHCCCCCCCC	67.05	-
680	Phosphorylation	SESKQKDYEENSWDT CHHHHCCCCCCCCCH	31.98	-
693	Phosphorylation	DTESLCETVSQKDVC CHHHHHHHHCCCCCC	25.18	-
695	Phosphorylation	ESLCETVSQKDVCLP HHHHHHHCCCCCCCC	38.64	-
720	Phosphorylation	INGKLEGSPVKDGLL HCCEECCCCCCCCHH	19.69	46164167
734	Ubiquitination	LKANCGMKVSIPTKA HHCCCCCEEECCHHH	20.36	21906983
736	Phosphorylation	ANCGMKVSIPTKALE CCCCCEEECCHHHHH	19.82	18491316
739	Phosphorylation	GMKVSIPTKALELMD CCEEECCHHHHHHHC	27.55	23612710
747	Phosphorylation	KALELMDMQTFKAEP HHHHHHCCHHCCCCC	2.23	27251275
749	Phosphorylation	LELMDMQTFKAEPPE HHHHCCHHCCCCCCC	22.07	18491316
752	Phosphorylation	MDMQTFKAEPPEKPS HCCHHCCCCCCCCCC	30.27	27251275
758	Phosphorylation	KAEPPEKPSAFEPAI CCCCCCCCCCCHHCH	29.27	27251275
783	Phosphorylation	LELKNEQTLRADEIL HHHCCCHHCCHHHCC	16.42	27251275
799	Phosphorylation	SESKQKDYEESSWDS CHHHCCCCHHCCCCH	28.73	-
803	Phosphorylation	QKDYEESSWDSESLC CCCCHHCCCCHHHHH	37.88	27251275
806	Phosphorylation	YEESSWDSESLCETV CHHCCCCHHHHHHHH	23.87	27251275
808	Phosphorylation	ESSWDSESLCETVSQ HCCCCHHHHHHHHCC	42.12	27251275
812	Phosphorylation	DSESLCETVSQKDVC CHHHHHHHHCCCCCC	25.18	-
814	Phosphorylation	ESLCETVSQKDVCLP HHHHHHHCCCCCCCC	38.64	27251275
839	Phosphorylation	INGKLEESPDNDGFL HCCEECCCCCCCCCC	28.33	113334327
855	Phosphorylation	APCRMKVSIPTKALE CCCEEEECCCHHHHH	19.82	18491316
858	Phosphorylation	RMKVSIPTKALELMD EEEECCCHHHHHHHC	27.55	23612710
868	Phosphorylation	LELMDMQTFKAEPPE HHHHCCCCCCCCCCC	22.07	18491316
963	Ubiquitination	EDSTSLSKILDTVHS CCCCHHHHHHHHHHH	53.21	-
986	Phosphorylation	KDHCEQRTGKMEQMK HHHHHHHCCHHHHHH	40.63	28258704
1019	Ubiquitination	QLENQKVKWEQELCS HHHHCCCCHHHHHHH	52.64	21906983
1109	Phosphorylation	HENCMLKKEIAMLKL CCCCHHHHHHHHHHH	50.85	-
1132	Phosphorylation	YQEKENKYFEDIKIL HHHHHCCHHHHHHHH	24.63	154593
1165	Phosphorylation	TKRASQYSGQLKVLI HHHHHHHHCCCEEEE	16.66	19664995

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AN30A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AN30A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AN30A_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of AN30A_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.