dbPTM

AMY1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	AMY1_MOUSE
UniProt AC	P00687
Protein Name	Alpha-amylase 1
Gene Name	Amy1
Organism	Mus musculus (Mouse).
Sequence Length	511
Subcellular Localization	Secreted.
Protein Description
Protein Sequence	MKFFLLLSLIGFCWAQYDPHTQYGRTAIVHLFEWRWVDIAKECERYLAPNGFAGVQVSPPNENIVVHSPSRPWWERYQPISYKICSRSGNEDEFRDMVNRCNNVGVRIYVDAVINHMCGVGAQAGQSSTCGSYFNPNNRDFPGVPYSGFDFNDGKCRTASGGIENYQDAAQVRDCRLSGLLDLALEKDYVRTKVADYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNTKWFSQGSRPFIFQEVIDLGGEAVSSNEYFGNGRVTEFKYGAKLGKVMRKWDGEKMSYLKNWGEGWGLMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYYWPRNFQNGKDVNDWVGPPNNNGKTKEVSINPDSTCGNDWICEHRWRQIRNMVAFRNVVNGQPFANWWDNDSNQVAFGRGNKGFIVFNNDDWALSETLQTGLPAGTYCDVISGDKVDGNCTGIKVYVGNDGKAHFSISNSAEDPFIAIHAESKI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Pyrrolidone_carboxylic_acid	LIGFCWAQYDPHTQY HHHHHHHHCCCCCCC	20.75	-
16	Pyrrolidone_carboxylic_acid	LIGFCWAQYDPHTQY HHHHHHHHCCCCCCC	20.75	-
26	Phosphorylation	PHTQYGRTAIVHLFE CCCCCCCEEEEEEEE	19.17	21082442
81	Phosphorylation	WERYQPISYKICSRS HHHCCCCCEEECCCC	27.36	23737553
178	Phosphorylation	QVRDCRLSGLLDLAL HHHHCHHHHHHHHHH	14.19	81018341
193	Ubiquitination	EKDYVRTKVADYMNH HCCHHHHHHHHHHHH	25.51	-
215	Ubiquitination	GFRLDASKHMWPGDI EEEEECHHCCCCHHH	38.92	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of AMY1_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of AMY1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of AMY1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
AKAP8_MOUSE	Akap8	physical	12414807

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of AMY1_MOUSE

Related Literatures of Post-Translational Modification