ALG2_MOUSE - dbPTM
ALG2_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ALG2_MOUSE
UniProt AC Q9DBE8
Protein Name Alpha-1,3/1,6-mannosyltransferase ALG2
Gene Name Alg2
Organism Mus musculus (Mouse).
Sequence Length 415
Subcellular Localization Membrane
Single-pass membrane protein .
Protein Description Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate..
Protein Sequence MAENLYRARSRVYSPSVLFLHPDMGIGGAERLVLDAALALQEYGCDVKIWTAHYDPNHCFIETRELSVQCAGDWLPRSLGWGGRGAAICSYVRMVFLALYVLFLSGEEFDVVVCDQVSACIPVFKLARRRKRVLFYCHFPDLLLTQRNSALKKFYRAPIDWIEEYTTGMADRILVNSQYTASVFKETFKTLSHRNPDVLYPSLNIGSFDLAIPEKIDDLVPKGKQFLFLSINRYERKKNLPLALRSLVQLRNRLPSQEWDKVHLFMAGGYDDRIPENVEHYKELKKMVQESDLERHVTFLRSFSDRQKISLLHGCLCVLYTPSNEHFGIVPLEAMYMQCPVIAVNNGGPLESIVHKVTGFLCEPDPVHFSEAMEKFIHKPSLKATMGLAGKARVAEKFSADAFADQLYQYVTKLV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
10PhosphorylationENLYRARSRVYSPSV
CHHHHHHHHCCCCCE		25.7218846507
13PhosphorylationYRARSRVYSPSVLFL
HHHHHHCCCCCEEEE		17.4718846507
14PhosphorylationRARSRVYSPSVLFLH
HHHHHCCCCCEEEEC		14.0818846507
16PhosphorylationRSRVYSPSVLFLHPD
HHHCCCCCEEEECCC		26.0518846507
165UbiquitinationPIDWIEEYTTGMADR
CCHHHHHHCCCCCCE		9.2327667366
185UbiquitinationQYTASVFKETFKTLS
HHHHHHHHHHHHHHH		54.4022790023
238UbiquitinationINRYERKKNLPLALR
EEHHHHHCCCCHHHH		70.6827667366
256PhosphorylationQLRNRLPSQEWDKVH
HHHHCCCCCCCCCEE		45.3718319177
291O-linked_GlycosylationLKKMVQESDLERHVT
HHHHHHHHHHHHHHH		30.3330059200
318UbiquitinationLLHGCLCVLYTPSNE
HHCCCEEEEECCCCC		2.7127667366
381PhosphorylationEKFIHKPSLKATMGL
HHHCCCCCHHHHHCC		47.5152836487
391UbiquitinationATMGLAGKARVAEKF
HHHCCCCHHHHHHHH		27.6727667366
397UbiquitinationGKARVAEKFSADAFA
CHHHHHHHHCHHHHH		34.5822790023
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ALG2_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ALG2_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ALG2_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ALG2_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ALG2_MOUSE

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Related Literatures of Post-Translational Modification

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