| UniProt ID | ALG14_HUMAN | |
|---|---|---|
| UniProt AC | Q96F25 | |
| Protein Name | UDP-N-acetylglucosamine transferase subunit ALG14 homolog | |
| Gene Name | ALG14 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 216 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Single-pass membrane protein . Nucleus membrane Single-pass membrane protein . |
|
| Protein Description | May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER.. | |
| Protein Sequence | MVCVLVLAAAAGAVAVFLILRIWVVLRSMDVTPRESLSILVVAGSGGHTTEILRLLGSLSNAYSPRHYVIADTDEMSANKINSFELDRADRDPSNMYTKYYIHRIPRSREVQQSWPSTVFTTLHSMWLSFPLIHRVKPDLVLCNGPGTCVPICVSALLLGILGIKKVIIVYVESICRVETLSMSGKILFHLSDYFIVQWPALKEKYPKSVYLGRIV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 38 | Phosphorylation | VTPRESLSILVVAGS CCCHHCEEEEEEECC | 24.13 | 46162257 | |
| 64 | Phosphorylation | GSLSNAYSPRHYVIA HHHCCCCCCCEEEEE | 17.04 | 20886841 | |
| 73 | Phosphorylation | RHYVIADTDEMSANK CEEEEECCCCCCCHH | 25.49 | 46162269 | |
| 77 | Phosphorylation | IADTDEMSANKINSF EECCCCCCCHHCCCE | 27.00 | 46162263 | |
| 80 | Ubiquitination | TDEMSANKINSFELD CCCCCCHHCCCEECC | 42.87 | - | |
| 99 | Ubiquitination | DPSNMYTKYYIHRIP CCCHHCHHHHEEECC | 20.69 | 22817900 | |
| 206 | Phosphorylation | WPALKEKYPKSVYLG CHHHHHHCCCCEEEE | 19.58 | 50564645 | |
| 211 | Phosphorylation | EKYPKSVYLGRIV-- HHCCCCEEEECCC-- | 15.55 | 50564653 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ALG14_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ALG14_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ALG14_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of ALG14_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| 616227 | Myasthenic syndrome, congenital, 15 (CMS15) | |||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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