dbPTM

ALFP3_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ALFP3_ARATH
UniProt AC	Q9ZU52
Protein Name	Fructose-bisphosphate aldolase 3, chloroplastic {ECO:0000305}
Gene Name	FBA3 {ECO:0000303\|PubMed:22561114}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	391
Subcellular Localization	Plastid, chloroplast, plastoglobule .
Protein Description	Plays a key role in glycolysis and gluconeogenesis..
Protein Sequence	MASASFVKPNTLSSPWIGQRSFAHTSASSSPPPRVSFAIRAGAYSDELVKTAKSIASPGRGILAIDESNATCGKRLASIGLDNTEDNRQAYRQLLLTTPGLGDYISGSILFEETLYQSTKDGKTFVDCLRDANIVPGIKVDKGLSPLAGSNEESWCQGLDGLASRSAEYYKQGARFAKWRTVVSVPCGPSALAVKEAAWGLARYAAISQDNGLVPIVEPEILLDGDHPIERTLEVAEKVWSEVFFYLAQNNVMFEGILLKPSMVTPGAEHKNKASPETVADFTLTMLKRRVPPAVPGIMFLSGGQSEAEATLNLNAMNQSPNPWHVSFSYARALQNSVLRTWQGKPEKIEASQKALLVRAKANSLAQLGKYSAEGENEDAKKGMFVKGYTY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
150	Phosphorylation	GLSPLAGSNEESWCQ CCCCCCCCCHHHHHH	-
208	Phosphorylation	LARYAAISQDNGLVP HHHHHHHHCCCCCEE	-
275	Phosphorylation	AEHKNKASPETVADF CCCCCCCCHHHHHHH	19880383
278	Phosphorylation	KNKASPETVADFTLT CCCCCHHHHHHHHHH	19880383
283	Phosphorylation	PETVADFTLTMLKRR HHHHHHHHHHHHHCC	19880383
285	Phosphorylation	TVADFTLTMLKRRVP HHHHHHHHHHHCCCC	19880383
364	Phosphorylation	LVRAKANSLAQLGKY HHHHHHHHHHHHHCC	25561503
387	"N6,N6,N6-trimethyllysine"	AKKGMFVKGYTY--- HHCCCEECCCCC---	-
387	Methylation	AKKGMFVKGYTY--- HHCCCEECCCCC---	22547063

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ALFP3_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
387	K	Methylation		22547063
Can be trimethylated at Lys-387 by LSMT-L, but the trimethylation has no effect in vitro.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ALFP3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ALFP3_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ALFP3_ARATH

Related Literatures of Post-Translational Modification