UniProt ID | ALBU_MOUSE | |
---|---|---|
UniProt AC | P07724 | |
Protein Name | Serum albumin | |
Gene Name | Alb | |
Organism | Mus musculus (Mouse). | |
Sequence Length | 608 | |
Subcellular Localization | Secreted. | |
Protein Description | Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.. | |
Protein Sequence | MKWVTFLLLLFVSGSAFSRGVFRREAHKSEIAHRYNDLGEQHFKGLVLIAFSQYLQKCSYDEHAKLVQEVTDFAKTCVADESAANCDKSLHTLFGDKLCAIPNLRENYGELADCCTKQEPERNECFLQHKDDNPSLPPFERPEAEAMCTSFKENPTTFMGHYLHEVARRHPYFYAPELLYYAEQYNEILTQCCAEADKESCLTPKLDGVKEKALVSSVRQRMKCSSMQKFGERAFKAWAVARLSQTFPNADFAEITKLATDLTKVNKECCHGDLLECADDRAELAKYMCENQATISSKLQTCCDKPLLKKAHCLSEVEHDTMPADLPAIAADFVEDQEVCKNYAEAKDVFLGTFLYEYSRRHPDYSVSLLLRLAKKYEATLEKCCAEANPPACYGTVLAEFQPLVEEPKNLVKTNCDLYEKLGEYGFQNAILVRYTQKAPQVSTPTLVEAARNLGRVGTKCCTLPEDQRLPCVEDYLSAILNRVCLLHEKTPVSEHVTKCCSGSLVERRPCFSALTVDETYVPKEFKAETFTFHSDICTLPEKEKQIKKQTALAELVKHKPKATAEQLKTVMDDFAQFLDTCCKAADKDTCFSTEGPNLVTRCKDALA | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
15 | Phosphorylation | LLLFVSGSAFSRGVF HHHHHCCCHHHCCCC | 20.73 | 51459279 | |
18 | Phosphorylation | FVSGSAFSRGVFRRE HHCCCHHHCCCCCHH | 28.04 | 46161845 | |
28 | Acetylation | VFRREAHKSEIAHRY CCCHHHHHHHHHHHH | 57.75 | 23576753 | |
29 | Phosphorylation | FRREAHKSEIAHRYN CCHHHHHHHHHHHHC | 25.11 | 51459271 | |
35 | Phosphorylation | KSEIAHRYNDLGEQH HHHHHHHHCHHCHHH | 11.80 | 25195567 | |
44 | Acetylation | DLGEQHFKGLVLIAF HHCHHHHCHHHHHHH | 49.57 | 7609767 | |
52 | Phosphorylation | GLVLIAFSQYLQKCS HHHHHHHHHHHHHCC | 14.64 | 27180971 | |
58 | S-palmitoylation | FSQYLQKCSYDEHAK HHHHHHHCCHHHHHH | 2.69 | 26165157 | |
60 | Nitration | QYLQKCSYDEHAKLV HHHHHCCHHHHHHHH | 34.52 | - | |
60 | Phosphorylation | QYLQKCSYDEHAKLV HHHHHCCHHHHHHHH | 34.52 | 15534371 | |
65 | Ubiquitination | CSYDEHAKLVQEVTD CCHHHHHHHHHHHHH | 51.61 | 22790023 | |
75 | Acetylation | QEVTDFAKTCVADES HHHHHHHHHHHCCHH | 42.31 | 21728379 | |
82 | Phosphorylation | KTCVADESAANCDKS HHHHCCHHHHCCCCH | 32.98 | - | |
88 | Acetylation | ESAANCDKSLHTLFG HHHHCCCCHHHHHHH | 58.05 | 7923455 | |
88 | Ubiquitination | ESAANCDKSLHTLFG HHHHCCCCHHHHHHH | 58.05 | 22790023 | |
89 | Phosphorylation | SAANCDKSLHTLFGD HHHCCCCHHHHHHHH | 16.48 | 23984901 | |
92 | Phosphorylation | NCDKSLHTLFGDKLC CCCCHHHHHHHHHHC | 29.13 | 23984901 | |
97 | Ubiquitination | LHTLFGDKLCAIPNL HHHHHHHHHCCCCCH | 45.93 | 22790023 | |
99 | S-palmitoylation | TLFGDKLCAIPNLRE HHHHHHHCCCCCHHH | 3.88 | 28526873 | |
114 | S-palmitoylation | NYGELADCCTKQEPE HCHHHHHHCCCCCCC | 2.36 | 28526873 | |
115 | S-palmitoylation | YGELADCCTKQEPER CHHHHHHCCCCCCCC | 5.69 | 28526873 | |
148 | S-palmitoylation | RPEAEAMCTSFKENP CHHHHHHHHHCCCCC | 3.57 | 28526873 | |
150 | Phosphorylation | EAEAMCTSFKENPTT HHHHHHHHCCCCCCC | 29.41 | 21183079 | |
203 | Phosphorylation | ADKESCLTPKLDGVK CCHHHCCCCCCCCHH | 23.78 | 59148729 | |
205 | Ubiquitination | KESCLTPKLDGVKEK HHHCCCCCCCCHHHH | 54.71 | 22790023 | |
210 | Succinylation | TPKLDGVKEKALVSS CCCCCCHHHHHHHHH | 60.05 | 23954790 | |
212 | Succinylation | KLDGVKEKALVSSVR CCCCHHHHHHHHHHH | 41.10 | 23954790 | |
212 | Ubiquitination | KLDGVKEKALVSSVR CCCCHHHHHHHHHHH | 41.10 | - | |
216 | Phosphorylation | VKEKALVSSVRQRMK HHHHHHHHHHHHHHC | 24.78 | 24719451 | |
223 | Acetylation | SSVRQRMKCSSMQKF HHHHHHHCCHHHHHH | 32.90 | 23806337 | |
223 | Succinylation | SSVRQRMKCSSMQKF HHHHHHHCCHHHHHH | 32.90 | 23806337 | |
229 | Acetylation | MKCSSMQKFGERAFK HCCHHHHHHHHHHHH | 46.85 | 21728379 | |
229 | Succinylation | MKCSSMQKFGERAFK HCCHHHHHHHHHHHH | 46.85 | - | |
229 | Succinylation | MKCSSMQKFGERAFK HCCHHHHHHHHHHHH | 46.85 | 23806337 | |
236 | Acetylation | KFGERAFKAWAVARL HHHHHHHHHHHHHHH | 41.87 | 21728379 | |
236 | Phosphoglycerylation | KFGERAFKAWAVARL HHHHHHHHHHHHHHH | 41.87 | - | |
236 | Succinylation | KFGERAFKAWAVARL HHHHHHHHHHHHHHH | 41.87 | 23954790 | |
236 | Ubiquitination | KFGERAFKAWAVARL HHHHHHHHHHHHHHH | 41.87 | - | |
244 | Phosphorylation | AWAVARLSQTFPNAD HHHHHHHHCCCCCCC | 22.94 | 27180971 | |
246 | Phosphorylation | AVARLSQTFPNADFA HHHHHHCCCCCCCHH | 37.37 | 23984901 | |
257 | Ubiquitination | ADFAEITKLATDLTK CCHHHHHHHHHHHHH | 41.61 | 22790023 | |
260 | Phosphorylation | AEITKLATDLTKVNK HHHHHHHHHHHHHCH | 41.81 | 27180971 | |
264 | Acetylation | KLATDLTKVNKECCH HHHHHHHHHCHHHCC | 51.62 | 23954790 | |
264 | Succinylation | KLATDLTKVNKECCH HHHHHHHHHCHHHCC | 51.62 | 23954790 | |
264 | Ubiquitination | KLATDLTKVNKECCH HHHHHHHHHCHHHCC | 51.62 | - | |
267 | Acetylation | TDLTKVNKECCHGDL HHHHHHCHHHCCCCH | 55.93 | 23201123 | |
267 | Malonylation | TDLTKVNKECCHGDL HHHHHHCHHHCCCCH | 55.93 | 26073543 | |
269 | S-nitrosylation | LTKVNKECCHGDLLE HHHHCHHHCCCCHHH | 1.91 | 22588120 | |
269 | S-palmitoylation | LTKVNKECCHGDLLE HHHHCHHHCCCCHHH | 1.91 | 28526873 | |
270 | S-nitrosylation | TKVNKECCHGDLLEC HHHCHHHCCCCHHHH | 4.16 | 22588120 | |
270 | S-palmitoylation | TKVNKECCHGDLLEC HHHCHHHCCCCHHHH | 4.16 | 28526873 | |
277 | S-nitrosylation | CHGDLLECADDRAEL CCCCHHHHCCCHHHH | 5.19 | 22588120 | |
277 | S-palmitoylation | CHGDLLECADDRAEL CCCCHHHHCCCHHHH | 5.19 | 28526873 | |
287 | Phosphorylation | DRAELAKYMCENQAT CHHHHHHHHHHCCCC | 11.03 | 27742792 | |
289 | S-palmitoylation | AELAKYMCENQATIS HHHHHHHHHCCCCHH | 3.94 | 28526873 | |
294 | Phosphorylation | YMCENQATISSKLQT HHHHCCCCHHHHHHH | 16.19 | 51459287 | |
297 | Phosphorylation | ENQATISSKLQTCCD HCCCCHHHHHHHHCC | 33.27 | 22817900 | |
301 | Phosphorylation | TISSKLQTCCDKPLL CHHHHHHHHCCCHHH | 26.07 | 22817900 | |
302 | S-nitrosylation | ISSKLQTCCDKPLLK HHHHHHHHCCCHHHH | 1.50 | 22588120 | |
302 | S-palmitoylation | ISSKLQTCCDKPLLK HHHHHHHHCCCHHHH | 1.50 | 26165157 | |
303 | S-nitrosylation | SSKLQTCCDKPLLKK HHHHHHHCCCHHHHH | 9.52 | 22588120 | |
305 | Acetylation | KLQTCCDKPLLKKAH HHHHHCCCHHHHHHH | 24.53 | 21728379 | |
305 | Malonylation | KLQTCCDKPLLKKAH HHHHHCCCHHHHHHH | 24.53 | 26073543 | |
305 | Ubiquitination | KLQTCCDKPLLKKAH HHHHHCCCHHHHHHH | 24.53 | - | |
309 | Acetylation | CCDKPLLKKAHCLSE HCCCHHHHHHHHHHH | 56.44 | 23201123 | |
315 | Phosphorylation | LKKAHCLSEVEHDTM HHHHHHHHHCCCCCC | 45.02 | 22817900 | |
359 | Phosphorylation | GTFLYEYSRRHPDYS HHHHHHHHHHCCCCC | 15.76 | 24719451 | |
360 | Dimethylation | TFLYEYSRRHPDYSV HHHHHHHHHCCCCCH | 39.77 | - | |
361 | Dimethylation | FLYEYSRRHPDYSVS HHHHHHHHCCCCCHH | 39.49 | - | |
365 | Nitration | YSRRHPDYSVSLLLR HHHHCCCCCHHHHHH | 18.54 | - | |
365 | Phosphorylation | YSRRHPDYSVSLLLR HHHHCCCCCHHHHHH | 18.54 | 27180971 | |
366 | Phosphorylation | SRRHPDYSVSLLLRL HHHCCCCCHHHHHHH | 16.77 | 21183079 | |
368 | Phosphorylation | RHPDYSVSLLLRLAK HCCCCCHHHHHHHHH | 13.83 | 27180971 | |
376 | Acetylation | LLLRLAKKYEATLEK HHHHHHHHHHHHHHH | 42.59 | 23954790 | |
376 | Ubiquitination | LLLRLAKKYEATLEK HHHHHHHHHHHHHHH | 42.59 | 22790023 | |
384 | S-nitrosylation | YEATLEKCCAEANPP HHHHHHHHHHHCCCC | 1.62 | 22588120 | |
385 | S-nitrosylation | EATLEKCCAEANPPA HHHHHHHHHHCCCCC | 5.93 | 22588120 | |
393 | S-nitrosylation | AEANPPACYGTVLAE HHCCCCCEEHHHHHH | 3.87 | 22588120 | |
413 | Ubiquitination | EEPKNLVKTNCDLYE CCCHHHHHCCCHHHH | 36.87 | 22790023 | |
416 | S-palmitoylation | KNLVKTNCDLYEKLG HHHHHCCCHHHHHHH | 4.64 | 28526873 | |
421 | Acetylation | TNCDLYEKLGEYGFQ CCCHHHHHHHHHCCC | 48.51 | 22902405 | |
425 | Nitration | LYEKLGEYGFQNAIL HHHHHHHHCCCCEEE | 22.80 | - | |
425 | Phosphorylation | LYEKLGEYGFQNAIL HHHHHHHHCCCCEEE | 22.80 | 27180971 | |
438 | Succinylation | ILVRYTQKAPQVSTP EEEEECCCCCCCCCH | 54.99 | 23954790 | |
438 | Ubiquitination | ILVRYTQKAPQVSTP EEEEECCCCCCCCCH | 54.99 | - | |
443 | Phosphorylation | TQKAPQVSTPTLVEA CCCCCCCCCHHHHHH | 24.34 | 22817900 | |
444 | Phosphorylation | QKAPQVSTPTLVEAA CCCCCCCCHHHHHHH | 22.80 | 28318527 | |
446 | Phosphorylation | APQVSTPTLVEAARN CCCCCCHHHHHHHHH | 43.45 | - | |
460 | Acetylation | NLGRVGTKCCTLPED HHCCCCCCCCCCCHH | 22.76 | 23806337 | |
460 | Succinylation | NLGRVGTKCCTLPED HHCCCCCCCCCCCHH | 22.76 | - | |
460 | Succinylation | NLGRVGTKCCTLPED HHCCCCCCCCCCCHH | 22.76 | 23806337 | |
460 | Ubiquitination | NLGRVGTKCCTLPED HHCCCCCCCCCCCHH | 22.76 | - | |
461 | S-palmitoylation | LGRVGTKCCTLPEDQ HCCCCCCCCCCCHHH | 1.84 | 26165157 | |
463 | Phosphorylation | RVGTKCCTLPEDQRL CCCCCCCCCCHHHCC | 55.61 | 24719451 | |
472 | S-nitrosylation | PEDQRLPCVEDYLSA CHHHCCCCHHHHHHH | 6.57 | 22588120 | |
472 | S-palmitoylation | PEDQRLPCVEDYLSA CHHHCCCCHHHHHHH | 6.57 | 28526873 | |
490 | Acetylation | RVCLLHEKTPVSEHV HHHHHCCCCCCCHHH | 47.59 | 7611599 | |
490 | Ubiquitination | RVCLLHEKTPVSEHV HHHHHCCCCCCCHHH | 47.59 | 22790023 | |
491 | Phosphorylation | VCLLHEKTPVSEHVT HHHHCCCCCCCHHHH | 26.41 | 23375375 | |
494 | Phosphorylation | LHEKTPVSEHVTKCC HCCCCCCCHHHHHHC | 24.16 | 28542873 | |
499 | Acetylation | PVSEHVTKCCSGSLV CCCHHHHHHCCCCHH | 31.96 | 68447 | |
499 | Ubiquitination | PVSEHVTKCCSGSLV CCCHHHHHHCCCCHH | 31.96 | 22790023 | |
500 | S-nitrosylation | VSEHVTKCCSGSLVE CCHHHHHHCCCCHHH | 1.31 | 22588120 | |
500 | S-palmitoylation | VSEHVTKCCSGSLVE CCHHHHHHCCCCHHH | 1.31 | 28526873 | |
501 | S-nitrosylation | SEHVTKCCSGSLVER CHHHHHHCCCCHHHC | 5.71 | 22588120 | |
501 | S-palmitoylation | SEHVTKCCSGSLVER CHHHHHHCCCCHHHC | 5.71 | 28526873 | |
502 | Phosphorylation | EHVTKCCSGSLVERR HHHHHHCCCCHHHCC | 40.67 | 24719451 | |
511 | S-nitrosylation | SLVERRPCFSALTVD CHHHCCCCCCEEEEC | 3.90 | 22588120 | |
511 | S-palmitoylation | SLVERRPCFSALTVD CHHHCCCCCCEEEEC | 3.90 | 28526873 | |
513 | Phosphorylation | VERRPCFSALTVDET HHCCCCCCEEEECCC | 29.14 | - | |
520 | Phosphorylation | SALTVDETYVPKEFK CEEEECCCCCCCCCC | 25.92 | 23882026 | |
521 | Phosphorylation | ALTVDETYVPKEFKA EEEECCCCCCCCCCC | 16.83 | 26026062 | |
524 | Acetylation | VDETYVPKEFKAETF ECCCCCCCCCCCCEE | 66.78 | 21728379 | |
535 | Phosphorylation | AETFTFHSDICTLPE CCEEEEECCCCCCCH | 25.20 | 51459295 | |
538 | S-nitrosylation | FTFHSDICTLPEKEK EEEECCCCCCCHHHH | 3.72 | 22588120 | |
538 | S-palmitoylation | FTFHSDICTLPEKEK EEEECCCCCCCHHHH | 3.72 | 28526873 | |
543 | Acetylation | DICTLPEKEKQIKKQ CCCCCCHHHHHHHHH | 69.17 | 23806337 | |
543 | Succinylation | DICTLPEKEKQIKKQ CCCCCCHHHHHHHHH | 69.17 | - | |
543 | Succinylation | DICTLPEKEKQIKKQ CCCCCCHHHHHHHHH | 69.17 | 23806337 | |
549 | Ubiquitination | EKEKQIKKQTALAEL HHHHHHHHHHHHHHH | 55.28 | 22790023 | |
551 | Phosphorylation | EKQIKKQTALAELVK HHHHHHHHHHHHHHH | 32.30 | 27180971 | |
558 | Acetylation | TALAELVKHKPKATA HHHHHHHHCCCCCCH | 59.54 | 23954790 | |
558 | Methylation | TALAELVKHKPKATA HHHHHHHHCCCCCCH | 59.54 | - | |
570 | Phosphorylation | ATAEQLKTVMDDFAQ CCHHHHHHHHHHHHH | 29.65 | 24719451 | |
582 | S-palmitoylation | FAQFLDTCCKAADKD HHHHHHHHHHHCCCC | 1.93 | 28526873 | |
583 | S-palmitoylation | AQFLDTCCKAADKDT HHHHHHHHHHCCCCC | 3.50 | 28526873 | |
588 | Acetylation | TCCKAADKDTCFSTE HHHHHCCCCCCCCCC | 50.65 | 23806337 | |
588 | Malonylation | TCCKAADKDTCFSTE HHHHHCCCCCCCCCC | 50.65 | 25418362 | |
588 | Succinylation | TCCKAADKDTCFSTE HHHHHCCCCCCCCCC | 50.65 | - | |
588 | Succinylation | TCCKAADKDTCFSTE HHHHHCCCCCCCCCC | 50.65 | 23806337 | |
590 | Phosphorylation | CKAADKDTCFSTEGP HHHCCCCCCCCCCCC | 22.61 | 23984901 | |
591 | S-nitrosylation | KAADKDTCFSTEGPN HHCCCCCCCCCCCCC | 3.48 | 22588120 | |
591 | S-palmitoylation | KAADKDTCFSTEGPN HHCCCCCCCCCCCCC | 3.48 | 28526873 | |
593 | Phosphorylation | ADKDTCFSTEGPNLV CCCCCCCCCCCCCHH | 27.91 | 25521595 | |
594 | Phosphorylation | DKDTCFSTEGPNLVT CCCCCCCCCCCCHHH | 25.39 | 22817900 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ALBU_MOUSE !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ALBU_MOUSE !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ALBU_MOUSE !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
Oops, there are no PPI records of ALBU_MOUSE !! |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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