dbPTM

ALA5_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ALA5_ARATH
UniProt AC	Q9SGG3
Protein Name	Probable phospholipid-transporting ATPase 5 {ECO:0000303\|PubMed:11402198}
Gene Name	ALA5 {ECO:0000303\|PubMed:11402198}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	1228
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description	Involved in transport of phospholipids..
Protein Sequence	MARGRIRSKLRLSLLYTFGCLRPATLEGQDSQPIQGPGFSRTVFCNQPHMHKKKPLRYRSNYVSTTRYNLITFFPKSLYEQFHRAANLYFLVAAILSVFPLSPFNKWSMIAPLVFVVGLSMLKEALEDWRRFMQDVKINARKTCVHKSDGVFRQRKWKKVSVGDIVKVEKDEFFPADLLLLSSSYEDGICYVETMNLDGETNLKVKRSLEVSLPLDDDESFKNFMATIRCEDPNPNLYTFVGNLEFERQTFPLDPSQILLRDSKLRNTTYVYGVVVFTGFDTKVMQNSTKSPSKRSRIERTMDYIIYTLLVLLILISCISSSGFAWETEFHMPKMWYLRPGEPIDFTNPINPIYAGVVHLITALLLYGYLIPISLYVSIEVVKVWQASFINQDLHMYDDESGVPANARTSNLNEELGQVHTILSDKTGTLTCNQMDFLKCSIAGTSYGVRSSEVEVAAAKQMAVDLEEHGEISSTPQSQTKVYGTWDSSRTQEIEVEGDNNYNTPRAPIKGFGFEDNRLMNGNWLRESQPNDILQFFRILAICHTAIPELNEETGKYTYEAESPDEASFLAAAREFGFEFFKRTQSSVFIRERFSGSGQIIEREYKVLNLLEFTSKRKRMTVIVRDEEGQILLLCKGADSIIFERLAKNGKTYLGPTTRHLTEYGEAGLRTLALAYRKLDEDEYAAWNSEFLKAKTSIGSDRDELLETGADMIEKELILIGATAVEDKLQKGVPQCIDKLAQAGLKLWVLTGDKMETAINIGFACSLLRQGMRQICITSMNSEGGSQDSKRVVKENILNQLTKAVQMVKLEKDPHAAFALIIDGKTLTYALEDDMKYQFLALAVDCASVICCRVSPKQKALVVRLVKEGTGKTTLAIGDGANDVGMIQEADIGVGISGVEGMQAVMASDFSIAQFRFLERLLVVHGHWCYKRIAQMICYFFYKNIAFGLTLFYFEAFTGFSGQSVYNDYYLLLFNVVLTSLPVIALGVFEQDVSSEICLQFPALYQQGTKNLFFDWSRILGWMCNGVYASLVIFFLNIGIIYSQAFRDNGQTADMDAVGTTMFTCIIWAANVQIALTMSHFTWIQHVLIWGSIGMWYLFVAIYSMMPPSYSGNIYRILDEILAPAPIYWMATLLVTVAAVLPYVAHIAFQRFLNPLDHHIIQEIKYYGRDIEDARLWTRERTKAREKTKIGFTARVDAKIRHLRSKLNKKQSNLSHFSAQDAMSPRSL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
220	Phosphorylation	LPLDDDESFKNFMAT CCCCCCHHHHHHHHE	48.81	24894044
441	Phosphorylation	QMDFLKCSIAGTSYG CCCEEECCCCCCCCC	17.56	25368622
445	Phosphorylation	LKCSIAGTSYGVRSS EECCCCCCCCCCCCH	15.11	25368622
446	Phosphorylation	KCSIAGTSYGVRSSE ECCCCCCCCCCCCHH	20.97	25368622
447	Phosphorylation	CSIAGTSYGVRSSEV CCCCCCCCCCCCHHH	21.34	25368622
485	Phosphorylation	SQTKVYGTWDSSRTQ HHCEEEEEECCCCCE	14.38	25561503
488	Phosphorylation	KVYGTWDSSRTQEIE EEEEEECCCCCEEEE	17.18	30407730
489	Phosphorylation	VYGTWDSSRTQEIEV EEEEECCCCCEEEEE	36.55	25561503
504	Phosphorylation	EGDNNYNTPRAPIKG ECCCCCCCCCCCCCC	12.09	30407730
1212	Phosphorylation	SKLNKKQSNLSHFSA HHHCCCCCCCCCCCH	48.93	25561503
1218	Phosphorylation	QSNLSHFSAQDAMSP CCCCCCCCHHHCCCC	21.42	30407730
1224	Phosphorylation	FSAQDAMSPRSL--- CCHHHCCCCCCC---	20.91	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ALA5_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ALA5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ALA5_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ALA5_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ALA5_ARATH

Related Literatures of Post-Translational Modification