AL1A7_MOUSE - dbPTM
AL1A7_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID AL1A7_MOUSE
UniProt AC O35945
Protein Name Aldehyde dehydrogenase, cytosolic 1
Gene Name Aldh1a7 {ECO:0000312|MGI:MGI:1347050}
Organism Mus musculus (Mouse).
Sequence Length 501
Subcellular Localization Cytoplasm .
Protein Description Can oxidize benzaldehyde, propionaldehyde and acetaldehyde (By similarity). No detectable activity with retinal..
Protein Sequence MSSPAQPAVPAPLANLKIQHTKIFINNEWHDSVSSKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATMESMNAGKVFAHAYLLDVEISIKALQYFAGWADKIHGQTIPSDGNIFTYTRREPIGVCGQIIPWNGPLIIFTWKLGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFPPGVVNIVPGYGPTAGGAISSHMDIDKVSFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDSAVEFAHQGVFFHQGQICVAASRLFVEESIYDEFVRRSVERAKKYILGNPLNSGINQGPQIDKEQHNKILGLIESGKKEGAKLECGGGRWGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSMDDVIKRANNTTYGLAAGVFTKDLDKAITVSSALQAGMVWVNCYLAVPVQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMQISQKNS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSSPAQPAV
------CCCCCCCCC		45.0627180971
2Acetylation------MSSPAQPAV
------CCCCCCCCC		45.06-
3Phosphorylation-----MSSPAQPAVP
-----CCCCCCCCCC		23.9827180971
17UbiquitinationPAPLANLKIQHTKIF
CCCCCCCEEEEEEEE		39.88-
17MalonylationPAPLANLKIQHTKIF
CCCCCCCEEEEEEEE		39.8826320211
36UbiquitinationWHDSVSSKKFPVLNP
CCHHCCCCCCCCCCC		51.42-
37MalonylationHDSVSSKKFPVLNPA
CHHCCCCCCCCCCCC		57.7726320211
57AcetylationCHVEEGDKADVDKAV
EECCCCCHHHHHHHH		58.2922733758
57MalonylationCHVEEGDKADVDKAV
EECCCCCHHHHHHHH		58.2926320211
62AcetylationGDKADVDKAVKAARQ
CCHHHHHHHHHHHHH		55.7322733758
62UbiquitinationGDKADVDKAVKAARQ
CCHHHHHHHHHHHHH		55.73-
79PhosphorylationQIGSPWRTMDASERG
HCCCCCCCCCHHHHH		18.61-
91MalonylationERGRLLNKLADLMER
HHHHHHHHHHHHHHH		45.0526320211
91AcetylationERGRLLNKLADLMER
HHHHHHHHHHHHHHH		45.0522733758
91UbiquitinationERGRLLNKLADLMER
HHHHHHHHHHHHHHH		45.05-
128AcetylationLDVEISIKALQYFAG
HHHHHHHHHHHHHHH		35.93-
252AcetylationTGSTEVGKLIKEAAG
ECCHHHHHHHHHHHC		52.8223954790
252UbiquitinationTGSTEVGKLIKEAAG
ECCHHHHHHHHHHHC		52.82-
255SuccinylationTEVGKLIKEAAGKSN
HHHHHHHHHHHCCCC		52.3023954790
255MalonylationTEVGKLIKEAAGKSN
HHHHHHHHHHHCCCC		52.3026320211
255UbiquitinationTEVGKLIKEAAGKSN
HHHHHHHHHHHCCCC		52.30-
260MalonylationLIKEAAGKSNLKRVT
HHHHHHCCCCCCEEE		31.2926320211
267PhosphorylationKSNLKRVTLELGGKS
CCCCCEEEEEECCCC		20.6722324799
329UbiquitinationRSVERAKKYILGNPL
HHHHHHHHHHCCCCC		36.22-
329MalonylationRSVERAKKYILGNPL
HHHHHHHHHHCCCCC		36.2226320211
338PhosphorylationILGNPLNSGINQGPQ
HCCCCCCCCCCCCCC		49.0581018223
348UbiquitinationNQGPQIDKEQHNKIL
CCCCCCCHHHHHHHH		61.99-
348MalonylationNQGPQIDKEQHNKIL
CCCCCCCHHHHHHHH		61.9926320211
353AcetylationIDKEQHNKILGLIES
CCHHHHHHHHHHHHC		36.86-
353UbiquitinationIDKEQHNKILGLIES
CCHHHHHHHHHHHHC		36.86-
362MalonylationLGLIESGKKEGAKLE
HHHHHCCCCCCCEEE		57.8626320211
362UbiquitinationLGLIESGKKEGAKLE
HHHHHCCCCCCCEEE		57.86-
363UbiquitinationGLIESGKKEGAKLEC
HHHHCCCCCCCEEEE		65.98-
367AcetylationSGKKEGAKLECGGGR
CCCCCCCEEEECCCC		56.5323201123
367MalonylationSGKKEGAKLECGGGR
CCCCCCCEEEECCCC		56.5326320211
378UbiquitinationGGGRWGNKGFFVQPT
CCCCCCCCCCEECCE		53.83-
378AcetylationGGGRWGNKGFFVQPT
CCCCCCCCCCEECCE		53.8323954790
378MalonylationGGGRWGNKGFFVQPT
CCCCCCCCCCEECCE		53.8326320211
388PhosphorylationFVQPTVFSNVTDEMR
EECCEEECCCCHHHH		26.5023984901
391PhosphorylationPTVFSNVTDEMRIAK
CEEECCCCHHHHHHH		30.4123984901
398UbiquitinationTDEMRIAKEEIFGPV
CHHHHHHHHHHHCHH		54.21-
398SuccinylationTDEMRIAKEEIFGPV
CHHHHHHHHHHHCHH		54.2123954790
398MalonylationTDEMRIAKEEIFGPV
CHHHHHHHHHHHCHH		54.2126320211
410UbiquitinationGPVQQIMKFKSMDDV
CHHHHHHHCCCHHHH		51.79-
410AcetylationGPVQQIMKFKSMDDV
CHHHHHHHCCCHHHH		51.7922733758
412MalonylationVQQIMKFKSMDDVIK
HHHHHHCCCHHHHHH		39.0826320211
412AcetylationVQQIMKFKSMDDVIK
HHHHHHCCCHHHHHH		39.0823954790
412UbiquitinationVQQIMKFKSMDDVIK
HHHHHHCCCHHHHHH		39.08-
413PhosphorylationQQIMKFKSMDDVIKR
HHHHHCCCHHHHHHH		30.4925521595
419AcetylationKSMDDVIKRANNTTY
CCHHHHHHHHHCCCC		45.35-
419UbiquitinationKSMDDVIKRANNTTY
CCHHHHHHHHHCCCC		45.35-
419SuccinylationKSMDDVIKRANNTTY
CCHHHHHHHHHCCCC		45.3523954790
435UbiquitinationLAAGVFTKDLDKAIT
EEEEEECCCHHHHHC		44.84-
435AcetylationLAAGVFTKDLDKAIT
EEEEEECCCHHHHHC		44.84-
484PhosphorylationELGEHGLYEYTELKT
CCCCCCCEEHHHHHH		16.1025521595
486PhosphorylationGEHGLYEYTELKTVA
CCCCCEEHHHHHHHH		7.61-
490UbiquitinationLYEYTELKTVAMQIS
CEEHHHHHHHHHHHH		34.42-
499UbiquitinationVAMQISQKNS-----
HHHHHHHHCC-----		52.98-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of AL1A7_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of AL1A7_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of AL1A7_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of AL1A7_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of AL1A7_MOUSE

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Related Literatures of Post-Translational Modification

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