AKRCB_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AKRCB_ARATH
• UniProt AC: Q9M338
• Protein Name: Aldo-keto reductase family 4 member C11
• Gene Name: AKR4C11
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 315
• Protein Description: Oxidoreductase that may act on a broad range of substrates such as ketosteroids, aldehydes, ketones and sugars..
• Protein Sequence: MADEIGFFQLNTGAKIPSVGLGTWQAAPGVVGDAVAAAVKIGYQHIDCASRYGNEIEIGKVLKKLFDDGVVKREKLFITSKIWLTDLDPPDVQDALNRTLQDLQLDYVDLYLMHWPVRLKKGTVDFKPENIMPIDIPSTWKAMEALVDSGKARAIGVSNFSTKKLSDLVEAARVPPAVNQVECHPSWQQHKLHEFCKSKGIHLSGYSPLGSPGTTWVKADVLKSPVIEMIAKEIGKSPAQTALRWGLQMGHSILPKSTNEGRIRENFDVLGWSIPKEMFDKFSKIEQARLVQGTSFVHETLSPYKTLEELWDGEI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MADEIGFFQ ------CCCCCEEEE	24.12	22223895
79	Phosphorylation	KREKLFITSKIWLTD CHHEEEEEEEEEECC	19.34	23172892
80	Phosphorylation	REKLFITSKIWLTDL HHEEEEEEEEEECCC	19.82	19880383
283	Phosphorylation	KEMFDKFSKIEQARL HHHHHHCHHHHHHHH	38.16	24894044
295	Phosphorylation	ARLVQGTSFVHETLS HHHHCCCCCHHCCCC	31.90	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AKRCB_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AKRCB_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AKRCB_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of AKRCB_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.