AHSA2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AHSA2_HUMAN
• UniProt AC: Q719I0
• Protein Name: Putative activator of 90 kDa heat shock protein ATPase homolog 2 {ECO:0000305}
• Gene Name: AHSA2P {ECO:0000312|HGNC:HGNC:20437}
• Organism: Homo sapiens (Human).
• Sequence Length: 299
• Protein Description: Co-chaperone that stimulates HSP90 ATPase activity..
• Protein Sequence: MAKWGQGNPHWIVEEREDGTNVNNWRWTERDATSLSKGKFQELLVGIVVENDAGRGEINELKQVEGEASCSSRKGKLIFFYEWNIKLGWKGIVKESGVKHKGLIEIPNLSEENEVDDTEVSLSKKKGDGVILKDLMKTAGTAKVREALGDYLKALKTEFTTGMILPTKAMATQELTVKRKLSGNTLQVQASSPVALGVRIPTVALHMMELFDTTVEQLYSIFTVKELTNKKIIMKWRCGNWPEEHYAMVALNFVPTLGQTELQLKEFLSICKEENMKFCWQKQHFEEIKGSLQLTPLNG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2 (in isoform 2)	Phosphorylation	-	19.13	24043423
5	Phosphorylation	---MAKWGQGNPHWI ---CCCCCCCCCCEE	25.47	15570572
5 (in isoform 3)	Phosphorylation	-	25.47	15570572
7 (in isoform 2)	Phosphorylation	-	45.78	24043423
8 (in isoform 2)	Phosphorylation	-	19.85	24043423
14 (in isoform 2)	Phosphorylation	-	42.05	24043423
81	Phosphorylation	KGKLIFFYEWNIKLG CCEEEEEEEEEEEEC	14.86	27067055
138	Phosphorylation	ILKDLMKTAGTAKVR EHHHHHHHCCCHHHH	19.16	25954137
141	Phosphorylation	DLMKTAGTAKVREAL HHHHHCCCHHHHHHH	22.35	25954137
157	Phosphorylation	DYLKALKTEFTTGMI HHHHHHCCCCCCCCC	36.86	29507054
160	Phosphorylation	KALKTEFTTGMILPT HHHCCCCCCCCCCCC	19.06	29507054
161	Phosphorylation	ALKTEFTTGMILPTK HHCCCCCCCCCCCCH	30.03	29507054
167	Phosphorylation	TTGMILPTKAMATQE CCCCCCCCHHHCCCE	28.17	13465497
213	Phosphorylation	HMMELFDTTVEQLYS HHHHHHHCHHHHHHH	25.96	28787133
214	Phosphorylation	MMELFDTTVEQLYSI HHHHHHCHHHHHHHH	24.72	46160879

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AHSA2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AHSA2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AHSA2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of AHSA2_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.