| UniProt ID | AGRE1_MOUSE | |
|---|---|---|
| UniProt AC | Q61549 | |
| Protein Name | Adhesion G protein-coupled receptor E1 | |
| Gene Name | Adgre1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 931 | |
| Subcellular Localization |
Cell membrane Multi-pass membrane protein . |
|
| Protein Description | Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development.. | |
| Protein Sequence | MWGFWLLLFWGFSGMYRWGMTTLPTLGQTLGGVNECQDTTTCPAYATCTDTTDSYYCTCKRGFLSSNGQTNFQGPGVECQDVNECLQSDSPCGPNSVCTNILGRAKCSCLRGFSSSTGKDWILGSLDNFLCADVDECLTIGICPKYSNCSNSVGSYSCTCQPGFVLNGSICEDEDECVTRDVCPEHATCHNTLGSYYCTCNSGLESSGGGPMFQGLDESCEDVDECSRNSTLCGPTFICINTLGSYSCSCPAGFSLPTFQILGHPADGNCTDIDECDDTCPLNSSCTNTIGSYFCTCHPGFASSNGQLNFKDLEVTCEDIDECTQDPLQCGLNSVCTNVPGSYICGCLPDFQMDPEGSQGYGNFNCKRILFKCKEDLILQSEQIQQCQAVQGRDLGYASFCTLVNATFTILDNTCENKSAPVSLQSAATSVSLVLEQATTWFELSKEETSTLGTILLETVESTMLAALLIPSGNASQMIQTEYLDIESKVINEECKENESINLAARGDKMNVGCFIIKESVSTGAPGVAFVSFAHMESVLNERFFEDGQSFRKLRMNSRVVGGTVTGEKKEDFSKPIIYTLQHIQPKQKSERPICVSWNTDVEDGRWTPSGCEIVEASETHTVCSCNRMANLAIIMASGELTMEFSLYIISHVGTVISLVCLALAIATFLLCRAVQNHNTYMHLHLCVCLFLAKILFLTGIDKTDNQTACAIIAGFLHYLFLACFFWMLVEAVMLFLMVRNLKVVNYFSSRNIKMLHLCAFGYGLPVLVVIISASVQPRGYGMHNRCWLNTETGFIWSFLGPVCMIITINSVLLAWTLWVLRQKLCSVSSEVSKLKDTRLLTFKAIAQIFILGCSWVLGIFQIGPLASIMAYLFTIINSLQGAFIFLIHCLLNRQVRDEYKKLLTRKTDLSSHSQTSGILLSSMPSTSKMG | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 146 | Phosphorylation | TIGICPKYSNCSNSV EEEECCCCCCCCCCC | - | ||
| 147 | Phosphorylation | IGICPKYSNCSNSVG EEECCCCCCCCCCCC | - | ||
| 148 | N-linked_Glycosylation | GICPKYSNCSNSVGS EECCCCCCCCCCCCC | - | ||
| 167 | N-linked_Glycosylation | CQPGFVLNGSICEDE ECCCEEEECCEECCC | - | ||
| 229 | N-linked_Glycosylation | DVDECSRNSTLCGPT CHHHHHCCCCCCCCE | - | ||
| 269 | N-linked_Glycosylation | LGHPADGNCTDIDEC EECCCCCCCCCHHHC | - | ||
| 283 | N-linked_Glycosylation | CDDTCPLNSSCTNTI CCCCCCCCCCCCCCC | - | ||
| 405 | N-linked_Glycosylation | ASFCTLVNATFTILD HHHHHHHHHEEEECC | - | ||
| 417 | N-linked_Glycosylation | ILDNTCENKSAPVSL ECCCCCCCCCCCCCH | - | ||
| 474 | N-linked_Glycosylation | ALLIPSGNASQMIQT HHHCCCCCHHHHHHH | - | ||
| 498 | N-linked_Glycosylation | INEECKENESINLAA HCHHHHHCCCCCCHH | - | ||
| 550 | Phosphorylation | RFFEDGQSFRKLRMN HHCCCCCCHHHHHCC | 24719451 | ||
| 706 | N-linked_Glycosylation | TGIDKTDNQTACAII HCCCCCCCHHHHHHH | - | ||
| 747 | Phosphorylation | RNLKVVNYFSSRNIK CCHHHHHHHHCCCCC | 29899451 | ||
| 750 | Phosphorylation | KVVNYFSSRNIKMLH HHHHHHHCCCCCHHH | 29899451 | ||
| 827 | Phosphorylation | VLRQKLCSVSSEVSK HHHHHHHCCCHHHHC | - | ||
| 833 | Phosphorylation | CSVSSEVSKLKDTRL HCCCHHHHCCCCCHH | - | ||
| 842 | Phosphorylation | LKDTRLLTFKAIAQI CCCCHHHHHHHHHHH | - | ||
| 908 | Phosphorylation | KKLLTRKTDLSSHSQ HHHHHHCCCCCCCCC | 29472430 | ||
| 911 | Phosphorylation | LTRKTDLSSHSQTSG HHHCCCCCCCCCCCC | 29472430 | ||
| 912 | Phosphorylation | TRKTDLSSHSQTSGI HHCCCCCCCCCCCCE | 29472430 | ||
| 914 | Phosphorylation | KTDLSSHSQTSGILL CCCCCCCCCCCCEEE | 24719451 | ||
| 916 | Phosphorylation | DLSSHSQTSGILLSS CCCCCCCCCCEEECC | 25159016 | ||
| 917 | Phosphorylation | LSSHSQTSGILLSSM CCCCCCCCCEEECCC | 25159016 | ||
| 922 | Phosphorylation | QTSGILLSSMPSTSK CCCCEEECCCCCCCC | 29472430 | ||
| 923 | Phosphorylation | TSGILLSSMPSTSKM CCCEEECCCCCCCCC | 29472430 | ||
| 926 | Phosphorylation | ILLSSMPSTSKMG-- EEECCCCCCCCCC-- | 25159016 | ||
| 927 | Phosphorylation | LLSSMPSTSKMG--- EECCCCCCCCCC--- | 29472430 | ||
| 928 | Phosphorylation | LSSMPSTSKMG---- ECCCCCCCCCC---- | 29899451 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of AGRE1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of AGRE1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of AGRE1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of AGRE1_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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