| UniProt ID | AGRB1_MOUSE | |
|---|---|---|
| UniProt AC | Q3UHD1 | |
| Protein Name | Adhesion G protein-coupled receptor B1 {ECO:0000312|MGI:MGI:1933736} | |
| Gene Name | Adgrb1 {ECO:0000312|MGI:MGI:1933736} | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 1582 | |
| Subcellular Localization |
Cell membrane Multi-pass membrane protein . Cell projection, phagocytic cup . Cell junction, focal adhesion . Cell projection, dendritic spine . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Vasculostatin-120: Secreted . V |
|
| Protein Description | Phosphatidylserine receptor which enhances the engulfment of apoptotic cells. [PubMed: 17960134 Also mediates the binding and engulfment of Gram-negative bacteria] | |
| Protein Sequence | MRGQAAAPGPIWILAPLLLLLLLLGRWARAASGADIGPGTEQCTTLVQGKFFGYFSAAAVFPANASRCSWTLRNPDPRRYTLYMKVAKAPAPCSGPGRVRTYQFDSFLESTRTYLGVESFDEVLRLCDSSAPLAFLQASKQFLQMQRQQPPQDGDLGPQGEFPSSSDDFSVEYLVVGNRNPSHAACQMLCRWLDACLAGSRSSHPCGIMQTPCACLGGDVGDPASSPLVPRGDVCLRDGVAGGPENCLTSLTQDRGGHGSAGGWKLWSLWGECTRDCGGGLQTRTRTCLPTLGVEGGGCEGVLEEGRLCNRKACGPTGRSSSRSQSLRSTDARRREEFGDELQQFGFPSPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFCNIALCPGRAVDGNWNEWSSWSTCSASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPVDGKWQAWASWGSCSVTCGGGSQRRERVCSGPFFGGAACQGPQDEYRQCGAQRCPEPHEICDEDNFGAVVWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAFWEPPTYIRCVSIDYRNIQMMTREHLAKAQRGLPGEGVSEVIQTLLEISQDGTSYSGDLLSTIDVLRNMTEIFRRAYYSPTPGDVQNFVQIISNLLAEENRDKWEEAQLMGPNAKELFRLVEDFVDVIGFRMKDLRDAYQVTDNLVLSIHKLPASGATDISFPMKGWRATGDWAKVPEDRVTVSKSVFSTGLAEADDSSVFVVGTVLYRNLGSFLALQRNTTVLNSKVISVTVKPPPRSLLTPLEIEFAHMYNGTTNQTCILWDETDGPSSSAPPQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADATMDKVTVPSVTLIVGCGVSSLTLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFLHFFFLSSFCWVLTEAWQSYMAVTGRLRSRLVRKRFLCLGWGLPALVVAISVGFTKAKGYSTMNYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQDAVKCRVVDRQEEGNGDSGGSFQNGHAQLMTDFEKDVDLACRSVLNKDIAACRTATITGTFKRPSLPEEEKMKLAKGPPPTFNSLPANVSKLHLHGSPRYPGGPLPDFPNHSLTLKKDKAPKSSFIGDGDIFKKLDSELSRAQEKALDTSYVILPTATATLRPKPKEEPKYSINIDQMPQTRLIHLSMAPDASFPTRSPPAREPPGGAPPEVPPVQPPPPPPPPPPPPQQPIPPPPTLEPAPPSLGDTGEPAAHPGPSSGAGAKNENVATLSVSSLERRKSRYAELDFEKIMHTRKRHQDMFQDLNRKLQHAAEKEKEVPGADSKPEKQQTPNKRAWESLRKPHGTPAWVKKELEPLPPSPLELRSVEWEKAGATIPLVGQDIIDLQTEV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 32 | Phosphorylation | GRWARAASGADIGPG HHHHHHHCCCCCCCC | 21454597 | ||
| 40 | Phosphorylation | GADIGPGTEQCTTLV CCCCCCCCHHCCHHC | 21454597 | ||
| 44 | Phosphorylation | GPGTEQCTTLVQGKF CCCCHHCCHHCCCCC | 21454597 | ||
| 64 | N-linked_Glycosylation | AAAVFPANASRCSWT EEEEEECCHHHCEEE | - | ||
| 81 | Phosphorylation | NPDPRRYTLYMKVAK CCCCCCEEEEEEEEC | - | ||
| 83 | Phosphorylation | DPRRYTLYMKVAKAP CCCCEEEEEEEECCC | - | ||
| 401 | N-linked_Glycosylation | LREQRLCNNSAVCPV CHHHCCCCCCCCCCC | - | ||
| 607 | N-linked_Glycosylation | AAVRCPRNATGLILR EEEECCCCCCEEEEE | - | ||
| 609 | Phosphorylation | VRCPRNATGLILRRC EECCCCCCEEEEEEC | 27180971 | ||
| 630 | Ubiquitination | IAFWEPPTYIRCVSI EEECCCCCEEEEEEE | 27667366 | ||
| 676 | Ubiquitination | LLEISQDGTSYSGDL HHHHCCCCCCCCCCH | 27667366 | ||
| 692 | N-linked_Glycosylation | STIDVLRNMTEIFRR HHHHHHHHHHHHHHH | - | ||
| 844 | N-linked_Glycosylation | SFLALQRNTTVLNSK HHHHHCCCCEEEECE | - | ||
| 877 | N-linked_Glycosylation | IEFAHMYNGTTNQTC EEEEECCCCCCCCEE | - | ||
| 881 | N-linked_Glycosylation | HMYNGTTNQTCILWD ECCCCCCCCEEEEEE | - | ||
| 911 | Phosphorylation | WSWRGCRTVPLDALR CCCCCCCEECHHHHH | 27180971 | ||
| 1114 | Ubiquitination | MVIGILVFNKLVSKD HHHHHHHHCHHHCCC | 27667366 | ||
| 1160 | Ubiquitination | AVLAVTDRRSALFQI HHHHHHCHHHHHHHH | 27667366 | ||
| 1210 | Phosphorylation | QEEGNGDSGGSFQNG CCCCCCCCCCCCCCC | 29899451 | ||
| 1213 | Phosphorylation | GNGDSGGSFQNGHAQ CCCCCCCCCCCCCEE | 29899451 | ||
| 1239 | Ubiquitination | ACRSVLNKDIAACRT HHHHHCCCCHHHCCE | 22790023 | ||
| 1257 | Phosphorylation | TGTFKRPSLPEEEKM EECCCCCCCCHHHHH | 25521595 | ||
| 1268 | Ubiquitination | EEKMKLAKGPPPTFN HHHHHHHCCCCCCCC | 22790023 | ||
| 1273 | Ubiquitination | LAKGPPPTFNSLPAN HHCCCCCCCCCCCCC | 27667366 | ||
| 1273 | Phosphorylation | LAKGPPPTFNSLPAN HHCCCCCCCCCCCCC | 22817900 | ||
| 1276 | Phosphorylation | GPPPTFNSLPANVSK CCCCCCCCCCCCCEE | 25521595 | ||
| 1282 | Phosphorylation | NSLPANVSKLHLHGS CCCCCCCEEEEECCC | 20415495 | ||
| 1289 | Phosphorylation | SKLHLHGSPRYPGGP EEEEECCCCCCCCCC | 22324799 | ||
| 1292 | Phosphorylation | HLHGSPRYPGGPLPD EECCCCCCCCCCCCC | 29899451 | ||
| 1301 | Ubiquitination | GGPLPDFPNHSLTLK CCCCCCCCCCCCEEC | 27667366 | ||
| 1303 | Ubiquitination | PLPDFPNHSLTLKKD CCCCCCCCCCEECCC | 27667366 | ||
| 1304 | Phosphorylation | LPDFPNHSLTLKKDK CCCCCCCCCEECCCC | 22324799 | ||
| 1305 | Ubiquitination | PDFPNHSLTLKKDKA CCCCCCCCEECCCCC | 27667366 | ||
| 1306 | Phosphorylation | DFPNHSLTLKKDKAP CCCCCCCEECCCCCC | 22324799 | ||
| 1306 | Ubiquitination | DFPNHSLTLKKDKAP CCCCCCCEECCCCCC | 27667366 | ||
| 1308 | Ubiquitination | PNHSLTLKKDKAPKS CCCCCEECCCCCCCC | 22790023 | ||
| 1314 | Ubiquitination | LKKDKAPKSSFIGDG ECCCCCCCCCCCCCH | 22790023 | ||
| 1319 | Ubiquitination | APKSSFIGDGDIFKK CCCCCCCCCHHHHHH | 27667366 | ||
| 1325 | Ubiquitination | IGDGDIFKKLDSELS CCCHHHHHHHHHHHH | 22790023 | ||
| 1341 | Phosphorylation | AQEKALDTSYVILPT HHHHHHCCCEEEEEC | - | ||
| 1347 | Ubiquitination | DTSYVILPTATATLR CCCEEEEECCCCCCC | 27667366 | ||
| 1349 | Ubiquitination | SYVILPTATATLRPK CEEEEECCCCCCCCC | 27667366 | ||
| 1350 | Phosphorylation | YVILPTATATLRPKP EEEEECCCCCCCCCC | - | ||
| 1351 | Ubiquitination | VILPTATATLRPKPK EEEECCCCCCCCCCC | 27667366 | ||
| 1352 | Ubiquitination | ILPTATATLRPKPKE EEECCCCCCCCCCCC | 27667366 | ||
| 1352 | Phosphorylation | ILPTATATLRPKPKE EEECCCCCCCCCCCC | - | ||
| 1364 | Phosphorylation | PKEEPKYSINIDQMP CCCCCCCEECCCCCC | 28059163 | ||
| 1462 | Phosphorylation | AKNENVATLSVSSLE CCCCCEEEEEHHHHH | 21183079 | ||
| 1464 | Phosphorylation | NENVATLSVSSLERR CCCEEEEEHHHHHHH | 29899451 | ||
| 1466 | Phosphorylation | NVATLSVSSLERRKS CEEEEEHHHHHHHHH | 22324799 | ||
| 1467 | Phosphorylation | VATLSVSSLERRKSR EEEEEHHHHHHHHHH | 25521595 | ||
| 1473 | Phosphorylation | SSLERRKSRYAELDF HHHHHHHHHHHCCCH | 29899451 | ||
| 1475 | Phosphorylation | LERRKSRYAELDFEK HHHHHHHHHCCCHHH | 29899451 | ||
| 1538 | Phosphorylation | SLRKPHGTPAWVKKE HHHCCCCCCHHHHHH | - | ||
| 1552 | Phosphorylation | ELEPLPPSPLELRSV HCCCCCCCCCEEEEE | 22817900 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of AGRB1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of AGRB1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of AGRB1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of AGRB1_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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