AGFG2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AGFG2_MOUSE
• UniProt AC: Q80WC7
• Protein Name: Arf-GAP domain and FG repeat-containing protein 2
• Gene Name: Agfg2
• Organism: Mus musculus (Mouse).
• Sequence Length: 479
• Protein Sequence: MVMAAKKGPGPGGGVGGSKAEAEAASEVWCRRVRELGGCSQAGNRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVLFLQSRGNEVCRKIWLGLFDARTSLIPDSRDPQKVKEFLQEKYEKKRWYVPPEQVKGPSYSKGSVSATPVQGSVPEGKPIRTLLGDPVPSLSDPASTSSQPGSQSQARSSSQARSSQPPSHSSTKKASTDLLADIGGDPFAAPQVVPAFASFPGFGVGQTPAHGGFANFDAFSSSPSSSTFGSLPPSVQAPFQAQPTPAGSGQMSAFGVAPLAAASQPNNLADVGGLLGPRMAAGGLPGSVFGMPSQVPALQSAVPGVSGSGGLPFGAYTNPFATPAQAQLPSTNPFQPNGLASGPGFGMSSVRPGLLQPVPPSGAFASPFSAPVFPTQAGLADQQNGSSFGDLGTSKLGQRPLSQPAGISTNPFMTGSSAFASKPPTTNPFL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Malonylation	-MVMAAKKGPGPGGG -CCCCCCCCCCCCCC	66.66	26320211
18	Phosphorylation	PGGGVGGSKAEAEAA CCCCCCCHHHHHHHH	23.82	29895711
85	Phosphorylation	NPPHRVKSISMTTFT CCCCCCCEEECEECC	19.62	26643407
87	Phosphorylation	PHRVKSISMTTFTEP CCCCCEEECEECCCC	19.71	26643407
89	Phosphorylation	RVKSISMTTFTEPEV CCCEEECEECCCCEE	16.39	29899451
132	Ubiquitination	SRDPQKVKEFLQEKY CCCHHHHHHHHHHHH	50.19	-
152	Ubiquitination	YVPPEQVKGPSYSKG CCCHHHCCCCCCCCC	65.87	-
158	Malonylation	VKGPSYSKGSVSATP CCCCCCCCCCCCCCC	47.15	26320211
158	Ubiquitination	VKGPSYSKGSVSATP CCCCCCCCCCCCCCC	47.15	-
160	Phosphorylation	GPSYSKGSVSATPVQ CCCCCCCCCCCCCCC	19.35	26060331
162	Phosphorylation	SYSKGSVSATPVQGS CCCCCCCCCCCCCCC	28.28	28066266
164	Phosphorylation	SKGSVSATPVQGSVP CCCCCCCCCCCCCCC	19.24	29472430
169	Phosphorylation	SATPVQGSVPEGKPI CCCCCCCCCCCCCCH	19.87	26060331
174	Ubiquitination	QGSVPEGKPIRTLLG CCCCCCCCCHHHHCC	35.29	-
174	Acetylation	QGSVPEGKPIRTLLG CCCCCCCCCHHHHCC	35.29	90221
186	Phosphorylation	LLGDPVPSLSDPAST HCCCCCCCCCCCCCC	40.51	25338131
188	Phosphorylation	GDPVPSLSDPASTSS CCCCCCCCCCCCCCC	45.98	25338131
219	Phosphorylation	SQPPSHSSTKKASTD CCCCCCCCCCCHHHH	38.53	25266776
220	Phosphorylation	QPPSHSSTKKASTDL CCCCCCCCCCHHHHH	39.31	25266776
451	Phosphorylation	KLGQRPLSQPAGIST CCCCCCCCCCCCCCC	36.48	27180971
457	Phosphorylation	LSQPAGISTNPFMTG CCCCCCCCCCCCCCC	22.63	23984901
458	Phosphorylation	SQPAGISTNPFMTGS CCCCCCCCCCCCCCC	45.02	23984901
463	Phosphorylation	ISTNPFMTGSSAFAS CCCCCCCCCCHHHCC	34.00	23984901
465	Phosphorylation	TNPFMTGSSAFASKP CCCCCCCCHHHCCCC	14.88	23984901
466	Phosphorylation	NPFMTGSSAFASKPP CCCCCCCHHHCCCCC	28.84	23984901

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AGFG2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AGFG2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AGFG2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of AGFG2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.