AGAP7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AGAP7_HUMAN
• UniProt AC: Q5VUJ5
• Protein Name: Putative Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 7
• Gene Name: AGAP7P
• Organism: Homo sapiens (Human).
• Sequence Length: 663
• Protein Description: Putative GTPase-activating protein..
• Protein Sequence: MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGEDLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSDGLSKDMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
218	Phosphorylation	PPTANTPTPVCKRSM CCCCCCCCCCCCHHH	26.73	27067055
224	Phosphorylation	PTPVCKRSMRWSNLF CCCCCCHHHCHHHHC	9.74	27067055
232	Phosphorylation	MRWSNLFTSEKGSDP HCHHHHCCCCCCCCC	38.86	-
281	Phosphorylation	LKTWKKKYVTLCSNG HHHCHHHEEEECCCC	13.93	7459045
299	Phosphorylation	YYSSLGDYMKYIHKK EHHHHHHHHHHHHHH	8.16	-
312	Phosphorylation	KKEIDLQTSTIKVPG HHCCCCCCCEEECCC	34.82	-
323	Phosphorylation	KVPGKWPSLATLACT ECCCCCCCCEEEEEC	29.53	26503514
326	Phosphorylation	GKWPSLATLACTPIS CCCCCCEEEEECCCC	21.85	26503514
330	Phosphorylation	SLATLACTPISSSKS CCEEEEECCCCCCCC	20.32	26503514
333	Phosphorylation	TLACTPISSSKSDGL EEEECCCCCCCCCCC	29.75	26503514
334	Phosphorylation	LACTPISSSKSDGLS EEECCCCCCCCCCCC	42.37	26503514
341	Phosphorylation	SSKSDGLSKDMDTGL CCCCCCCCCCCCCCC	31.94	-
417	Phosphorylation	AWVQAIQSQILASLQ HHHHHHHHHHHHHHH	17.05	-
431	Phosphorylation	QSCESSKSKSQLTSQ HHHCCCCCHHHCCCH	39.21	29888752
433	Phosphorylation	CESSKSKSQLTSQSE HCCCCCHHHCCCHHH	37.20	29888752
436	Phosphorylation	SKSKSQLTSQSEAMA CCCHHHCCCHHHHHH	19.65	29888752
437	Phosphorylation	KSKSQLTSQSEAMAL CCHHHCCCHHHHHHH	40.06	29888752
439	Phosphorylation	KSQLTSQSEAMALQS HHHCCCHHHHHHHHH	27.39	29888752
446	Phosphorylation	SEAMALQSIQNMRGN HHHHHHHHHHHHCCC	27.30	29888752
529	Phosphorylation	EGSSQGRTKPTEKST CCCCCCCCCCCCCCC	48.47	-
532	Phosphorylation	SQGRTKPTEKSTREE CCCCCCCCCCCCHHH	58.56	-
546	Phosphorylation	EKERWIRSKYEEKLF HHHHHHHHHHHHHHC	30.38	23401153
603	Phosphorylation	CGEGDGCTALHLACR CCCCCCCHHHHHHHH	37.47	23403867

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AGAP7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AGAP7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AGAP7_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of AGAP7_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.