dbPTM

AFP2_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	AFP2_ARATH
UniProt AC	Q9LMX5
Protein Name	Ninja-family protein AFP2
Gene Name	AFP2
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	348
Subcellular Localization	Nucleus .
Protein Description	Acts as a negative regulator of abscisic acid (ABA) response during germination through the ubiquitin-mediated proteolysis of ABI5/DPBF1..
Protein Sequence	MGEASRQQRAWNREMTVTTNLSLDIDKYPRDLLRGFMSENGGGRVFHGGETNCDDESTIELNLGLSLGGRFGVDKTPRKLKRSSSVLDTVPFNDSTVAEPENYTVGLERTTSLPAEMEEEWRKRKEMQSLRRMEAKRRRCEKQSFRVGNSDDQTVSFENERWVTASKSGFLQRHLVSSNRQVCGVDSDGGGATGGGSSSSLSELDNKNQQGSSNSCNDERSPKIVAGCSSNSGSQGTERPSVTRANKVNENENEKRVRSEDSVDRKGKGMATSTGLVDMPCVFTKGDGPNGRRVDGILYKYGKGEEVRIMCICHGSFLTPAEFVKHGGGGDVDRPLRHIVVNTSSSTF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
76	Phosphorylation	GRFGVDKTPRKLKRS CCCCCCCCCHHHCCC	24.70	25561503
110	Phosphorylation	YTVGLERTTSLPAEM EEECEEECCCCCHHH	16.03	27288362
111	Phosphorylation	TVGLERTTSLPAEME EECEEECCCCCHHHH	34.19	27288362
112	Phosphorylation	VGLERTTSLPAEMEE ECEEECCCCCHHHHH	31.57	30291188
232	Phosphorylation	VAGCSSNSGSQGTER EEECCCCCCCCCCCC	41.59	25561503
234	Phosphorylation	GCSSNSGSQGTERPS ECCCCCCCCCCCCCC	25.84	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of AFP2_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of AFP2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of AFP2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
ABI5_ARATH	ABI5	physical	24823379

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of AFP2_ARATH

Related Literatures of Post-Translational Modification