ADT4_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ADT4_MOUSE
• UniProt AC: Q3V132
• Protein Name: ADP/ATP translocase 4
• Gene Name: Slc25a31
• Organism: Mus musculus (Mouse).
• Sequence Length: 320
• Subcellular Localization: Mitochondrion inner membrane; Multi-pass membrane protein. Cell projection, cilium, flagellum. In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region..
• Protein Description: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility..
• Protein Sequence: MSNESSKKQSSKKALFDPVSFSKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMLDCLVRIPREQGFLSYWRGNLANVIRYFPTQALNFAFKDKYKELFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEQRQFTGLGDCIMKIAKSDGLIGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKETPFLVSFIIAQIVTTCSGILSYPFDTVRRRMMMQSGESDRQYKGTIDCFLKIYRHEGVPAFFRGAFSNILRGTGGALVLVLYDKIKEFLNIDVGGSSSGD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Phosphorylation	VAAAVSKTAVAPIER HHHHCCCCCCCCHHH	20.89	28542873
94	Phosphorylation	NLANVIRYFPTQALN CHHHHHHHCCHHHHH	11.64	24925903
97	Phosphorylation	NVIRYFPTQALNFAF HHHHHCCHHHHHHHC	19.30	24925903
105	Acetylation	QALNFAFKDKYKELF HHHHHHCHHHHHHHH	50.29	6568297
105	Ubiquitination	QALNFAFKDKYKELF HHHHHHCHHHHHHHH	50.29	-
107	Acetylation	LNFAFKDKYKELFMS HHHHCHHHHHHHHHH	59.83	7617837
193	Phosphorylation	LYQGFGVSVQGIIVY ECCCCCEEEEEEEEE	14.76	26487105
200	Phosphorylation	SVQGIIVYRASYFGA EEEEEEEEEEHHHCC	7.05	26487105
204	Phosphorylation	IIVYRASYFGAYDTV EEEEEEHHHCCHHHH	12.68	-
293	Phosphorylation	FSNILRGTGGALVLV HHHHHHCCCCEEEEE	26.47	20495213
316	Phosphorylation	LNIDVGGSSSGD--- HCCCCCCCCCCC---	18.53	25293948
317	Phosphorylation	NIDVGGSSSGD---- CCCCCCCCCCC----	41.43	25293948
318	Phosphorylation	IDVGGSSSGD----- CCCCCCCCCC-----	48.99	25293948

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ADT4_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ADT4_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ADT4_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ADT4_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.