UniProt ID | ADRB3_HUMAN | |
---|---|---|
UniProt AC | P13945 | |
Protein Name | Beta-3 adrenergic receptor | |
Gene Name | ADRB3 | |
Organism | Homo sapiens (Human). | |
Sequence Length | 408 | |
Subcellular Localization |
Cell membrane Multi-pass membrane protein. |
|
Protein Description | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.. | |
Protein Sequence | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRVGADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRGELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGTFTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLLCRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
8 | N-linked_Glycosylation | MAPWPHENSSLAPWP CCCCCCCCCCCCCCC | 33.59 | UniProtKB CARBOHYD | |
26 | N-linked_Glycosylation | TLAPNTANTSGLPGV CCCCCCCCCCCCCCC | 32.51 | UniProtKB CARBOHYD | |
153 | S-palmitoylation | GALVTKRCARTAVVL CHHHHHHHHCHHHHH | 2.99 | 30541923 | |
292 | S-palmitoylation | LREHRALCTLGLIMG HHHHHHHHHHHHHHH | 2.63 | 30541923 | |
361 | S-palmitoylation | SAFRRLLCRCGRRLP HHHHHHHHHCCCCCC | 3.91 | 30541923 | |
363 | S-palmitoylation | FRRLLCRCGRRLPPE HHHHHHHCCCCCCCC | 4.92 | 30541923 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ADRB3_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ADRB3_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ADRB3_HUMAN !! |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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