dbPTM

ADCK1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ADCK1_MOUSE
UniProt AC	Q9D0L4
Protein Name	Uncharacterized aarF domain-containing protein kinase 1
Gene Name	Adck1
Organism	Mus musculus (Mouse).
Sequence Length	525
Subcellular Localization	Secreted .
Protein Description	The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)..
Protein Sequence	MARKALKLASWTSVALAASGVYLYSNNYLDPNDFGAVRVGRAVATTAVISYDYLTSLRSVPYGSEEYLQRRSQVHLRSARRLFELCCANRGTFIKVGQHLGALDYLLPEEYTSTLKVLHSQAPQSSMQEVRQVIREDLGKEIHDLFLSFDDTPLGAASLAQVHKAVLHDGRTVAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFPDFEFMWLVDEAKKNLPLELDFLNEGRNAEKVAHMLRHFDFLKVPQIHWELSTKRVLLMEFVEGGQVNDRAYMEKNQIDVNEISCHLGKMYSEMIFVNGFVHCDPHPGNVLVRKRPDTGKAEIVLLDHGLYQVLTEEFRLDYCHLWQSLIWTDMDGLKQYSQRLGAADLYPLFACMLTARSWDSVKQGIGQAPVSATEDSEIRNNAACYLPEISQLLNHVPRQMLLILKTNDLLRSIETTLGTRSSASSFLNMSRCCIRALAEHKKRDAGSFFRRTQISFSEAFSLWQINLHELLLRVRALRLACWVSALLGWLTRAPHRM

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
449	Phosphorylation	ETTLGTRSSASSFLN HHHHCCCCCHHHHHH	30.05	29899451
450	Phosphorylation	TTLGTRSSASSFLNM HHHCCCCCHHHHHHH	28.95	29899451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ADCK1_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ADCK1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ADCK1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ADCK1_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ADCK1_MOUSE

Related Literatures of Post-Translational Modification