ADA32_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ADA32_MOUSE
• UniProt AC: Q8K410
• Protein Name: Disintegrin and metalloproteinase domain-containing protein 32
• Gene Name: Adam32
• Organism: Mus musculus (Mouse).
• Sequence Length: 754
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Description: May play a role in sperm development and fertilization This is a non-catalytic metalloprotease-like protein..
• Protein Sequence: MLGAMLHTLLLLLLAELGALLASGPESQSSFLEIIFPEKIEDKTHSEEQISYIIPINKKQYTVHLQKRYFLTNRFMVYMYNQGSTSFHSPNIPAQCYYQGHIKGYPNSVATLSTCSGLRGFLQFENVSYGIEPLQSAFTSQHIVYKLGNKEKELIFNKNSRNIEMPTNYGILINKKPKSPFKNLFPLYLEMSIVVDKALYDYLGSDSNIVTNKIIEIISLINSVFAQLKVTIVLSSLELWSDKNKIPTVGEADELLHKFLEWKQAYLTLRPHDVAYLFIYNEYPNYMGATYPGKMCTAHYSAGITMYPKDMTLEAFSVILTQMLGLSLGISYDEPEKCYCSESICIMNPRAMQYGGVKSFSNCSLNDFEHFKSNEGAKCLQNKPQMQRTAAAVCGNGKVEGDEICDCGSEAECGPDSCCEPNRCVLKAGRACDSKSPSSTCCKNCQFLPEKHQCRPEKHLYCDIPEVCNGSSGNCPPDVTINNGHVCKESGTICYNGDCPDLDRVCESIYGAGSVNAPFACYEEIQGQNDRFGNCGKDNRNRYVFCGWRNLICGRLICTYPTRMPYNPPNNSTASVIYAFVRDKVCITVDFGSSVKEDPLRVANGATCDLDRICLNGVCVESRFLRDQSKTCSSKCHGNGVCNSHGVCHCNAGYSPPNCQYPTTKRSASLWSGKHDLPMERASKNQEKKWLLSLYIVLIILASVFLIGTGWKGLKQCGSKEEESMSSESKSEDSTYTYVSRSTSETSSMTSTSS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	ELGALLASGPESQSS HHHHHHHCCCCHHHC	55.65	-
61	Phosphorylation	IPINKKQYTVHLQKR EECCCCEEEEEEEEE	21.43	21454597
62	Phosphorylation	PINKKQYTVHLQKRY ECCCCEEEEEEEEEE	10.04	28576409
126	N-linked_Glycosylation	RGFLQFENVSYGIEP CCEEEEECCCCCCCC	29.35	-
362	N-linked_Glycosylation	GGVKSFSNCSLNDFE CCCCCCCCCCHHCCH	19.86	-
469	N-linked_Glycosylation	CDIPEVCNGSSGNCP ECCHHHCCCCCCCCC	59.56	-
570	N-linked_Glycosylation	RMPYNPPNNSTASVI CCCCCCCCCCCHHHH	57.23	-
571	N-linked_Glycosylation	MPYNPPNNSTASVIY CCCCCCCCCCHHHHE	46.65	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ADA32_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ADA32_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ADA32_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ADA32_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.