| UniProt ID | ADA23_MOUSE | |
|---|---|---|
| UniProt AC | Q9R1V7 | |
| Protein Name | Disintegrin and metalloproteinase domain-containing protein 23 | |
| Gene Name | Adam23 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 829 | |
| Subcellular Localization |
Cell membrane Single-pass type I membrane protein . Isoform Gamma: Secreted. |
|
| Protein Description | May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein (By similarity).. | |
| Protein Sequence | MKPPGSISRRPTLTGCSLPGASCGPGRCPAGPVPARAPPCRLLLVLLLLPALATSSRPRARGAAAPSAPHWNETAEKTLGVLADEDNTLQQNSSSRNTSYSSAVQKEITLPSRLVYYINQDSESPYHVLDTKARHQQKHNKAVHLAQASFQIEAFGSKFILDLTLNNGLLSSDYVEIHYEDGKQMYSKGGEHCYYHGSIRGVKDSRVALSTCNGLHGMFEDDTFVYMIEPLELTDDEKSTGRPHIIQKTLAGQYSKQMKNLSTDGSDQWPLLPELQWLRRRKRAVNPSRGVFEEMKYLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKEQLNTRVVLVAVETWTEKDHIDITINPVQMLHDFSKYRQRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRIRGVGVNEYGLPMAVAQVLSQSLAQNLGIQWEPSSRKPKCECIESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCGFHVECYGVCCKKCSLSNGAHCSDGPCCNNTSCLFQSRGYECRDAVNSCDITEYCTGDSGQCPPNLHKQDGYSCNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTEGTEKGNCGKDGDRWIPCSKHDVFCGFLLCTNLTRAPRIGQLQGEIIPTSFYHQGRVIDCSGAHVVLDDDTDVGYVEDGTPCGPSMMCLDRKCLQIQALNMSSCPLDSRGKVCSGHGVCSNEATCICDFTWAGTDCSIRDPVRNPNPPKDEGPKGPSATNLIIGSIAGAILVAAIVLGGTGWGFKNVKKRRFDPTQQGPI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 72 | N-linked_Glycosylation | APSAPHWNETAEKTL CCCCCCCHHHHHHHH | 33.44 | - | |
| 92 | N-linked_Glycosylation | EDNTLQQNSSSRNTS CCCCCCCCCCCCCCC | 30.79 | - | |
| 97 | N-linked_Glycosylation | QQNSSSRNTSYSSAV CCCCCCCCCCHHHHH | 35.01 | - | |
| 186 | Phosphorylation | YEDGKQMYSKGGEHC EECCCEEEECCCCCC | 12.53 | 26026062 | |
| 260 | N-linked_Glycosylation | QYSKQMKNLSTDGSD HHHHHHHCCCCCCCC | 33.60 | - | |
| 288 | Phosphorylation | RKRAVNPSRGVFEEM HHHCCCCCCCHHHHH | 36.14 | 52836349 | |
| 297 | Phosphorylation | GVFEEMKYLELMIVN CHHHHHHHEEEEEEC | 12.23 | 52836355 | |
| 390 | Phosphorylation | VHLISRVTFHYKRSS HHHHHHHHCCCCCCC | 12.00 | 101545111 | |
| 393 | Phosphorylation | ISRVTFHYKRSSLSY HHHHHCCCCCCCCCC | 12.14 | 11255595 | |
| 400 | Phosphorylation | YKRSSLSYFGGVCSR CCCCCCCCCCCCCHH | 16.13 | 28576409 | |
| 544 | N-linked_Glycosylation | CSDGPCCNNTSCLFQ CCCCCCCCCCCHHEE | 62.62 | - | |
| 545 | N-linked_Glycosylation | SDGPCCNNTSCLFQS CCCCCCCCCCHHEEC | 21.32 | - | |
| 661 | N-linked_Glycosylation | CGFLLCTNLTRAPRI HHHEEECCCCCCCCH | 38.12 | - | |
| 717 | S-palmitoylation | PCGPSMMCLDRKCLQ CCCCCHHCCCCHHEE | 2.40 | 28680068 | |
| 729 | N-linked_Glycosylation | CLQIQALNMSSCPLD HEEEEECCCCCCCCC | 31.16 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ADA23_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ADA23_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ADA23_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of ADA23_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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