ACT4_CAEEL - dbPTM
ACT4_CAEEL - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ACT4_CAEEL
UniProt AC P10986
Protein Name Actin-4
Gene Name act-4
Organism Caenorhabditis elegans.
Sequence Length 376
Subcellular Localization Cytoplasm, cytoskeleton .
Protein Description Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells..
Protein Sequence MCDDEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGVVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITVGNERFRCPEALFQPSFLGMESAGIHETSYNSIMKCDIDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
3Acetylation-----MCDDEVAALV
-----CCCCCCEEEE		54.53-
34PhosphorylationAPRAVFPSIVGRPRH
CCCCCCHHHCCCCCC		20.5928854356
53PhosphorylationVGMGQKDSYVGDEAQ
EECCCCCCCCCCHHH		28.8422923814
54PhosphorylationGMGQKDSYVGDEAQS
ECCCCCCCCCCHHHC		20.7027067626
61PhosphorylationYVGDEAQSKRGILTL
CCCCHHHCCCCEEEE		31.2230078680
107PhosphorylationEEHPVLLTEAPLNPK
CCCCEEEEECCCCCC		26.4128854356
167PhosphorylationVTHTVPIYEGYALPH
CEEEEEEECCCCCCH		9.3827067626
170PhosphorylationTVPIYEGYALPHAIL
EEEEECCCCCCHHHH		7.9427067626
199PhosphorylationKILTERGYSFTTTAE
HHHHHCCCCCCCCHH		13.5627067626
233PhosphorylationQEMATAASSSSLEKS
HHHHHHHCCCCCCCE		28.4330078680
234PhosphorylationEMATAASSSSLEKSY
HHHHHHCCCCCCCEE		21.1530078680
235PhosphorylationMATAASSSSLEKSYE
HHHHHCCCCCCCEEE		36.1330078680
236PhosphorylationATAASSSSLEKSYEL
HHHHCCCCCCCEEEC		42.3630078680
240PhosphorylationSSSSLEKSYELPDGQ
CCCCCCCEEECCCCC		17.9230078680
241PhosphorylationSSSLEKSYELPDGQV
CCCCCCEEECCCCCE		32.3327067626
298PhosphorylationRKDLYANTVLSGGTT
CCHHHCCCEECCCCC		18.0430078680
301PhosphorylationLYANTVLSGGTTMYP
HHCCCEECCCCCCCC		30.7330078680
304PhosphorylationNTVLSGGTTMYPGIA
CCEECCCCCCCCCHH		16.3530078680
305PhosphorylationTVLSGGTTMYPGIAD
CEECCCCCCCCCHHH		20.2730078680
324PhosphorylationEITALAPSTMKIKII
HHHHHCCCCEEEEEE		35.2130078680
325PhosphorylationITALAPSTMKIKIIA
HHHHCCCCEEEEEEC		22.7930078680
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ACT4_CAEEL !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ACT4_CAEEL !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ACT4_CAEEL !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ACT2_CAEELact-2physical
18692475
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ACT4_CAEEL

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Related Literatures of Post-Translational Modification

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